-transparent.png){kind=logo}
In vitamin D-fed chicks 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 were implanted into experimentally-produced fractures of the mid-tibia. The mechanical and biochemical properties of the tibia were evaluated for two weeks, including torsion tests, measurement of alkaline phosphatase activity, 45Ca incorporation, and Ca2+ content. Both dihydroxylated metabolites of vitamin D3 had a direct effect on endochondral bone formation. 24,25(OH)2D3 strengthened the callus, and raised alkaline phosphate activity in the first seven days after fracture. 1,25(OH)2D3 decreased the strength of the callus concomitant with a reduction in 45Ca incorporation. It is suggested that local application of 24,25(OH)2D3 into fractures may accelerate healing and prevent non-union.
C Lidor, and
S Dekel, and
M S Meyer, and
E Blaugrund, and
T Hallel, and
S Edelstein
February 1980,
British medical journal,
C Lidor, and
S Dekel, and
M S Meyer, and
E Blaugrund, and
T Hallel, and
S Edelstein
August 1981,
The Journal of clinical endocrinology and metabolism,
C Lidor, and
S Dekel, and
M S Meyer, and
E Blaugrund, and
T Hallel, and
S Edelstein
September 1982,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
C Lidor, and
S Dekel, and
M S Meyer, and
E Blaugrund, and
T Hallel, and
S Edelstein
September 1978,
Science (New York, N.Y.),
C Lidor, and
S Dekel, and
M S Meyer, and
E Blaugrund, and
T Hallel, and
S Edelstein
January 1984,
Calcified tissue international,
C Lidor, and
S Dekel, and
M S Meyer, and
E Blaugrund, and
T Hallel, and
S Edelstein
May 1984,
Biochemical pharmacology,
C Lidor, and
S Dekel, and
M S Meyer, and
E Blaugrund, and
T Hallel, and
S Edelstein
March 1980,
Clinical chemistry,
C Lidor, and
S Dekel, and
M S Meyer, and
E Blaugrund, and
T Hallel, and
S Edelstein
December 1998,
Clinical orthopaedics and related research,
C Lidor, and
S Dekel, and
M S Meyer, and
E Blaugrund, and
T Hallel, and
S Edelstein
January 1989,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
C Lidor, and
S Dekel, and
M S Meyer, and
E Blaugrund, and
T Hallel, and
S Edelstein
May 1992,
Biochemical pharmacology,
