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Neurological disorders associated with glutamic acid decarboxylase antibodies: a Brazilian series. 2012
Maurício Fernandes, and
Renato P Munhoz, and
Paulo Eduardo Mestrinelli Carrilho, and
Walter O Arruda, and
Paulo J Lorenzoni, and
Rosana H Scola, and
Lineu César Werneck, and
Hélio A G Teive
Movement Disorders Unit, Neurology Service, Internal Medicine Department, Hospital de Clínicas, Universidade Federal do Paraná (UFPR), Curitiba PR, Brazil.
Neurological disorders associated with glutamic acid decarboxylase (GAD) antibodies are rare pleomorphic diseases of uncertain cause, of which stiff-person syndrome (SPS) is the best-known. Here, we described nine consecutive cases of neurological disorders associated with anti-GAD, including nine patients with SPS and three cases with cerebellar ataxia. Additionally, four had hypothyroidism, three epilepsy, two diabetes mellitus and two axial myoclonus.
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