A Case of Light Chain Deposition Disease (LCDD) in a Young Patient. 2011

Mala Mahto, and Sudhesna Mohapatra, and G Sumitra, and Smita Kaushik, and T K Mishra, and Alpana Saxena
Department of Biochemistry, Maulana Azad Medical College, New Delhi, 110002 India.

Light chain disease is a variant of multiple myeloma in which the malignant population of marrow cells produces free monoclonal light chains but no heavy chain or complete immunoglobulin. The monoclonal light chains are small enough to be freely filtered by the kidneys and become Bence-Jones protein. Light chain disease comprises about 18% of multiple myeloma patients. Here we present a case report of a 38-year-old man who initially presented with complaints of pain in back and low grade fever off and on. He was found to have collapse of D9 and D12 vertebrae along with ascites and right pleural effusion and massive proteinuria. Multiple myeloma was considered as a differential diagnosis based on the investigations but eventually the patient was lost to follow up. This case is reported here as the light chain variant of multiple myeloma leading to deposition disease is less commonly reported and presents considerable difficulties in diagnosis.

UI MeSH Term Description Entries

Related Publications

Mala Mahto, and Sudhesna Mohapatra, and G Sumitra, and Smita Kaushik, and T K Mishra, and Alpana Saxena
January 1997, Ryoikibetsu shokogun shirizu,
Mala Mahto, and Sudhesna Mohapatra, and G Sumitra, and Smita Kaushik, and T K Mishra, and Alpana Saxena
August 1985, Pathology, research and practice,
Mala Mahto, and Sudhesna Mohapatra, and G Sumitra, and Smita Kaushik, and T K Mishra, and Alpana Saxena
December 2020, Gan to kagaku ryoho. Cancer & chemotherapy,
Mala Mahto, and Sudhesna Mohapatra, and G Sumitra, and Smita Kaushik, and T K Mishra, and Alpana Saxena
September 2021, Leukemia & lymphoma,
Mala Mahto, and Sudhesna Mohapatra, and G Sumitra, and Smita Kaushik, and T K Mishra, and Alpana Saxena
January 1994, Ultrastructural pathology,
Mala Mahto, and Sudhesna Mohapatra, and G Sumitra, and Smita Kaushik, and T K Mishra, and Alpana Saxena
April 1988, Acta pathologica japonica,
Mala Mahto, and Sudhesna Mohapatra, and G Sumitra, and Smita Kaushik, and T K Mishra, and Alpana Saxena
January 1989, Pathologica,
Mala Mahto, and Sudhesna Mohapatra, and G Sumitra, and Smita Kaushik, and T K Mishra, and Alpana Saxena
May 2012, Indian journal of nephrology,
Mala Mahto, and Sudhesna Mohapatra, and G Sumitra, and Smita Kaushik, and T K Mishra, and Alpana Saxena
March 2016, The American journal of case reports,
Mala Mahto, and Sudhesna Mohapatra, and G Sumitra, and Smita Kaushik, and T K Mishra, and Alpana Saxena
June 2022, Cureus,
Copied contents to your clipboard!