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Supernatant fluids (SNF) were obtained from peritoneal exudate adherent cells stimulated in vitro with sheep red blood cells (SRBC) or BCG, and SNF collected at 6 and 24 hr were able to induce the migratory responses of rat leukocytes from the spleen and peripheral blood. The production of these SNF was dependent on protein active synthesis upon in vitro antigenic stimulation. The chemotactic activity from 6-hr SNF was inhibited by using several proteolytic enzymes and temperatures. We found the macrophages to be the producer cell of this activity, while the T cells were the target cells. The chemotactic activity from 6-hr SNF was found not to be due to IL-1. Six-hour chemotactic activity has not been reported previously.
R Gomez-Flores, and
C Rodriguez-Padilla, and
R Tamez-Guerra
October 1983,
Pediatric research,
R Gomez-Flores, and
C Rodriguez-Padilla, and
R Tamez-Guerra
June 1993,
Immunology letters,
R Gomez-Flores, and
C Rodriguez-Padilla, and
R Tamez-Guerra
June 1983,
Journal of immunology (Baltimore, Md. : 1950),
R Gomez-Flores, and
C Rodriguez-Padilla, and
R Tamez-Guerra
June 1975,
Annals of the New York Academy of Sciences,
R Gomez-Flores, and
C Rodriguez-Padilla, and
R Tamez-Guerra
September 1986,
European journal of pharmacology,
R Gomez-Flores, and
C Rodriguez-Padilla, and
R Tamez-Guerra
March 1985,
Immunology,
R Gomez-Flores, and
C Rodriguez-Padilla, and
R Tamez-Guerra
December 1986,
British journal of experimental pathology,
R Gomez-Flores, and
C Rodriguez-Padilla, and
R Tamez-Guerra
August 1997,
British journal of pharmacology,
R Gomez-Flores, and
C Rodriguez-Padilla, and
R Tamez-Guerra
February 1979,
Chest,
R Gomez-Flores, and
C Rodriguez-Padilla, and
R Tamez-Guerra
January 1987,
The American review of respiratory disease,
