Three-dimensional ultrasound in the prenatal diagnosis of osteogenesis imperfecta. 2012

Pei-Yin Tsai, and Chiung-Hsin Chang, and Chen-Hsiang Yu, and Yueh-Chin Cheng, and Fong-Ming Chang
Department of Obstetrics and Gynecology, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan.

OBJECTIVE Fetal osteogenesis imperfecta (OI) is a heterogeneous group of collagen disorders characterized by bone fragility, blue sclerae, deafness, and dentinogenesis imperfecta. Ultrasonography is acknowledged as a reliable diagnostic modality for the prenatal diagnosis of OI, especially type II. In the past, two-dimensional (2D) ultrasound (US) has been applied as the mainstay of prenatal diagnosis of OI. In this series, we report our work of detecting OI using three-dimensional (3D) US. METHODS We reviewed our computer database of prenatal diagnosis of OI at the National Cheng Kung University Hospital from April 1996 to July 2010. All the cases were scanned by 2D and 3D US. In total, six cases of fetal OI were diagnosed. RESULTS Compared with 2D US, 3D US can detect fetal OI precisely, and provide additional vivid illustration after various modes of reconstruction that 2D US cannot. CONCLUSIONS In conclusion, 3D US may contribute significantly to the detection of OI in utero and provide a novel visual depiction of this defect after reconstruction. The technique may thus substantially assist in prenatal diagnosis as well as consultations for fetal OI.

UI MeSH Term Description Entries
D010013 Osteogenesis Imperfecta COLLAGEN DISEASES characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. Most types are autosomal dominant and are associated with mutations in COLLAGEN TYPE I. Fragilitas Ossium,Lobstein Disease,Brittle Bone Disease,Lobstein's Disease,Osteogenesis Imperfecta Tarda,Osteogenesis Imperfecta with Blue Sclerae,Osteogenesis Imperfecta, Type 1,Osteogenesis Imperfecta, Type I,Disease, Lobstein,Disease, Lobstein's,Lobsteins Disease,Ossiums, Fragilitas,Osteogenesis Imperfecta Tardas
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011262 Pregnancy Trimester, Second The middle third of a human PREGNANCY, from the beginning of the 15th through the 28th completed week (99 to 196 days) of gestation. Midtrimester,Pregnancy, Second Trimester,Trimester, Second,Midtrimesters,Pregnancies, Second Trimester,Pregnancy Trimesters, Second,Second Pregnancy Trimester,Second Pregnancy Trimesters,Second Trimester,Second Trimester Pregnancies,Second Trimester Pregnancy,Second Trimesters,Trimesters, Second
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D016216 Ultrasonography, Prenatal The visualization of tissues during pregnancy through recording of the echoes of ultrasonic waves directed into the body. The procedure may be applied with reference to the mother or the fetus and with reference to organs or the detection of maternal or fetal disease. Fetal Ultrasonography,Prenatal Diagnosis, Ultrasonic,Ultrasonography, Fetal,Diagnosis, Prenatal Ultrasonic,Diagnosis, Ultrasonic Prenatal,Prenatal Ultrasonic Diagnosis,Prenatal Ultrasonography,Ultrasonic Diagnosis, Prenatal,Ultrasonic Prenatal Diagnosis,Diagnoses, Prenatal Ultrasonic,Diagnoses, Ultrasonic Prenatal,Prenatal Diagnoses, Ultrasonic,Prenatal Ultrasonic Diagnoses,Ultrasonic Diagnoses, Prenatal,Ultrasonic Prenatal Diagnoses
D021621 Imaging, Three-Dimensional The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object. Computer-Assisted Three-Dimensional Imaging,Imaging, Three-Dimensional, Computer Assisted,3-D Image,3-D Imaging,Computer-Generated 3D Imaging,Three-Dimensional Image,Three-Dimensional Imaging, Computer Generated,3 D Image,3 D Imaging,3-D Images,3-D Imagings,3D Imaging, Computer-Generated,3D Imagings, Computer-Generated,Computer Assisted Three Dimensional Imaging,Computer Generated 3D Imaging,Computer-Assisted Three-Dimensional Imagings,Computer-Generated 3D Imagings,Image, 3-D,Image, Three-Dimensional,Images, 3-D,Images, Three-Dimensional,Imaging, 3-D,Imaging, Computer-Assisted Three-Dimensional,Imaging, Computer-Generated 3D,Imaging, Three Dimensional,Imagings, 3-D,Imagings, Computer-Assisted Three-Dimensional,Imagings, Computer-Generated 3D,Imagings, Three-Dimensional,Three Dimensional Image,Three Dimensional Imaging, Computer Generated,Three-Dimensional Images,Three-Dimensional Imaging,Three-Dimensional Imaging, Computer-Assisted,Three-Dimensional Imagings,Three-Dimensional Imagings, Computer-Assisted

Related Publications

Pei-Yin Tsai, and Chiung-Hsin Chang, and Chen-Hsiang Yu, and Yueh-Chin Cheng, and Fong-Ming Chang
June 2011, The journal of obstetrics and gynaecology research,
Pei-Yin Tsai, and Chiung-Hsin Chang, and Chen-Hsiang Yu, and Yueh-Chin Cheng, and Fong-Ming Chang
January 1988, Annals of the New York Academy of Sciences,
Pei-Yin Tsai, and Chiung-Hsin Chang, and Chen-Hsiang Yu, and Yueh-Chin Cheng, and Fong-Ming Chang
December 1994, Revue francaise de gynecologie et d'obstetrique,
Pei-Yin Tsai, and Chiung-Hsin Chang, and Chen-Hsiang Yu, and Yueh-Chin Cheng, and Fong-Ming Chang
April 1995, Acta obstetricia et gynecologica Scandinavica,
Pei-Yin Tsai, and Chiung-Hsin Chang, and Chen-Hsiang Yu, and Yueh-Chin Cheng, and Fong-Ming Chang
June 2004, Presse medicale (Paris, France : 1983),
Pei-Yin Tsai, and Chiung-Hsin Chang, and Chen-Hsiang Yu, and Yueh-Chin Cheng, and Fong-Ming Chang
February 1991, Prenatal diagnosis,
Pei-Yin Tsai, and Chiung-Hsin Chang, and Chen-Hsiang Yu, and Yueh-Chin Cheng, and Fong-Ming Chang
July 1988, American journal of obstetrics and gynecology,
Pei-Yin Tsai, and Chiung-Hsin Chang, and Chen-Hsiang Yu, and Yueh-Chin Cheng, and Fong-Ming Chang
February 1975, American journal of obstetrics and gynecology,
Pei-Yin Tsai, and Chiung-Hsin Chang, and Chen-Hsiang Yu, and Yueh-Chin Cheng, and Fong-Ming Chang
January 1983, Human genetics,
Pei-Yin Tsai, and Chiung-Hsin Chang, and Chen-Hsiang Yu, and Yueh-Chin Cheng, and Fong-Ming Chang
April 2006, Current opinion in obstetrics & gynecology,
Copied contents to your clipboard!