Although many visual stimulus databases exist, none has data on item similarity levels for multiple items of each kind of stimulus. We present such data for 50 sets of grayscale object photographs. Similarity measures between pictures in each set (e.g., 25 different buttons) were collected using a similarity-sorting method (Goldstone, Behavior Research Methods Instruments & Computers, 26(4):381-386, 1994). A validation experiment used data from 1 picture set and compared responses from standard pairwise measures. This showed close agreement. The similarity-sorting measures were then standardized across picture sets, using pairwise ratings. Finally, the standardized similarity distances were validated in a recognition memory experiment; false alarms increased when targets and foils were more similar. These data will facilitate memory and perception research that needs to make comparisons between stimuli with a range of known target-foil similarities.