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Bone mineral density increases in HIV-infected children treated with long-term combination antiretroviral therapy. 2013
Madeleine J Bunders, and
Olivier Frinking, and
Henriette J Scherpbier, and
Lotus A van Arnhem, and
Berthe L van Eck-Smit, and
Taco W Kuijpers, and
Aeilko H Zwinderman, and
Peter Reiss, and
Dasja Pajkrt
Department of Paediatric Immunology, Haematology, and Infectious Diseases, Emma Children Hospital, Amsterdam, The Netherlands. m.j.bunders@amc.uva.nl
The long-term treatment of human immunodeficiency virus (HIV)-infected children with combination antiretroviral therapy (cART) requires assessment of potential adverse effects, such as osteoporosis. Longitudinal data on bone mineral density (BMD) in HIV-infected children showed that cumulative treatment with cART had a positive impact on BMD over time.
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