[Cognitive deficit in schizophrenia: MATRICS Consensus Cognitive Battery]. 2012

Roberto Rodríguez-Jiménez, and Alexandra Bagney, and Marta Moreno-Ortega, and Cristina García-Navarro, and Ana Isabel Aparicio, and Raúl López-Antón, and José de la Oliva, and Miguel Ángel Jiménez-Arriero, and José Luis Santos, and Antonio Lobo, and Tomás Palomo
Servicio de Psiquiatría; Instituto de Investigación Hospital 12 de Octubre, i+12, Madrid, España. roberto.rodriguez.jimenez@gmail.com

Cognitive deficits constitute a core symptom in schizophrenia, are difficult to treat, and have special relevance regarding prognosis and functional outcome. The search for pharmacological strategies for improving cognition in schizophrenic patients has been hindered by the lack of a consensus regarding instruments for cognitive assessment. The 'Measurement and Treatment Research to Improve Cognition in Schizophrenia' (MATRICS) initiative of the U.S. National Institute of Mental Health (NIMH) set the development of a consensus cognitive battery as one of its objectives. In a first phase, the seven cognitive domains which have been shown to be impaired in schizophrenia and that were to be assessed were identified: Speed of processing, Attention/Vigilance, Working memory, Verbal learning, Visual learning, Reasoning and problem solving, and Social cognition. In a second phase, the MATRICS Consensus Cognitive Battery (MCCB) was developed. This is a cognitive assessment battery composed of ten instruments, which assess the seven domains in a little over one hour. The MCCB has been standardized in U.S. population, and the Spanish standardization has been recently published.

UI MeSH Term Description Entries
D007858 Learning Relatively permanent change in behavior that is the result of past experience or practice. The concept includes the acquisition of knowledge. Phenomenography
D008568 Memory Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.
D009315 National Institute of Mental Health (U.S.) A component of the NATIONAL INSTITUTES OF HEALTH concerned with research, overall planning, promoting, and administering mental health programs and research. It was established in 1949. NIMH,National Institute of Mental Health,United States National Institute of Mental Health
D009483 Neuropsychological Tests Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury. Aphasia Tests,Cognitive Test,Cognitive Testing,Cognitive Tests,Memory for Designs Test,Neuropsychological Testing,AX-CPT,Behavioral Assessment of Dysexecutive Syndrome,CANTAB,Cambridge Neuropsychological Test Automated Battery,Clock Test,Cognitive Function Scanner,Continuous Performance Task,Controlled Oral Word Association Test,Delis-Kaplan Executive Function System,Developmental Neuropsychological Assessment,Hooper Visual Organization Test,NEPSY,Neuropsychologic Tests,Neuropsychological Test,Paced Auditory Serial Addition Test,Repeatable Battery for the Assessment of Neuropsychological Status,Rey-Osterrieth Complex Figure,Symbol Digit Modalities Test,Test of Everyday Attention,Test, Neuropsychological,Tests, Neuropsychological,Tower of London Test,Neuropsychologic Test,Test, Cognitive,Testing, Cognitive,Testing, Neuropsychological,Tests, Cognitive
D011340 Problem Solving A learning situation involving more than one alternative from which a selection is made in order to attain a specific goal.
D003072 Cognition Disorders Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment. Overinclusion,Disorder, Cognition,Disorders, Cognition
D003245 Consensus Development Conferences as Topic Works that are about the concept of consensus development conferences, such as their general design or a means of scientific communication. Conferences, Consensus Statement as Topic,Consensus Statement Conferences as Topic,Consensus Workshops,Conferences, Consensus Development as Topic,Consensus Workshop,Workshop, Consensus,Workshops, Consensus
D005163 Factor Analysis, Statistical A set of statistical methods for analyzing the correlations among several variables in order to estimate the number of fundamental dimensions that underlie the observed data and to describe and measure those dimensions. It is used frequently in the development of scoring systems for rating scales and questionnaires. Analysis, Factor,Analysis, Statistical Factor,Factor Analysis,Statistical Factor Analysis,Analyses, Factor,Analyses, Statistical Factor,Factor Analyses,Factor Analyses, Statistical,Statistical Factor Analyses
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001288 Attention Focusing on certain aspects of current experience to the exclusion of others. It is the act of heeding or taking notice or concentrating. Focus of Attention,Selective Attention,Social Attention,Attention Focus,Attention, Selective,Attention, Social,Selective Attentions

Related Publications

Roberto Rodríguez-Jiménez, and Alexandra Bagney, and Marta Moreno-Ortega, and Cristina García-Navarro, and Ana Isabel Aparicio, and Raúl López-Antón, and José de la Oliva, and Miguel Ángel Jiménez-Arriero, and José Luis Santos, and Antonio Lobo, and Tomás Palomo
January 2020, Schizophrenia research,
Roberto Rodríguez-Jiménez, and Alexandra Bagney, and Marta Moreno-Ortega, and Cristina García-Navarro, and Ana Isabel Aparicio, and Raúl López-Antón, and José de la Oliva, and Miguel Ángel Jiménez-Arriero, and José Luis Santos, and Antonio Lobo, and Tomás Palomo
May 2013, Schizophrenia research,
Roberto Rodríguez-Jiménez, and Alexandra Bagney, and Marta Moreno-Ortega, and Cristina García-Navarro, and Ana Isabel Aparicio, and Raúl López-Antón, and José de la Oliva, and Miguel Ángel Jiménez-Arriero, and José Luis Santos, and Antonio Lobo, and Tomás Palomo
November 2011, Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology,
Roberto Rodríguez-Jiménez, and Alexandra Bagney, and Marta Moreno-Ortega, and Cristina García-Navarro, and Ana Isabel Aparicio, and Raúl López-Antón, and José de la Oliva, and Miguel Ángel Jiménez-Arriero, and José Luis Santos, and Antonio Lobo, and Tomás Palomo
December 2016, Psychiatry research,
Roberto Rodríguez-Jiménez, and Alexandra Bagney, and Marta Moreno-Ortega, and Cristina García-Navarro, and Ana Isabel Aparicio, and Raúl López-Antón, and José de la Oliva, and Miguel Ángel Jiménez-Arriero, and José Luis Santos, and Antonio Lobo, and Tomás Palomo
January 2023, Current topics in behavioral neurosciences,
Roberto Rodríguez-Jiménez, and Alexandra Bagney, and Marta Moreno-Ortega, and Cristina García-Navarro, and Ana Isabel Aparicio, and Raúl López-Antón, and José de la Oliva, and Miguel Ángel Jiménez-Arriero, and José Luis Santos, and Antonio Lobo, and Tomás Palomo
August 2014, Schizophrenia research,
Roberto Rodríguez-Jiménez, and Alexandra Bagney, and Marta Moreno-Ortega, and Cristina García-Navarro, and Ana Isabel Aparicio, and Raúl López-Antón, and José de la Oliva, and Miguel Ángel Jiménez-Arriero, and José Luis Santos, and Antonio Lobo, and Tomás Palomo
September 2017, Scientific reports,
Roberto Rodríguez-Jiménez, and Alexandra Bagney, and Marta Moreno-Ortega, and Cristina García-Navarro, and Ana Isabel Aparicio, and Raúl López-Antón, and José de la Oliva, and Miguel Ángel Jiménez-Arriero, and José Luis Santos, and Antonio Lobo, and Tomás Palomo
May 2017, Psychiatry and clinical neurosciences,
Roberto Rodríguez-Jiménez, and Alexandra Bagney, and Marta Moreno-Ortega, and Cristina García-Navarro, and Ana Isabel Aparicio, and Raúl López-Antón, and José de la Oliva, and Miguel Ángel Jiménez-Arriero, and José Luis Santos, and Antonio Lobo, and Tomás Palomo
July 2020, Psychological medicine,
Roberto Rodríguez-Jiménez, and Alexandra Bagney, and Marta Moreno-Ortega, and Cristina García-Navarro, and Ana Isabel Aparicio, and Raúl López-Antón, and José de la Oliva, and Miguel Ángel Jiménez-Arriero, and José Luis Santos, and Antonio Lobo, and Tomás Palomo
January 2012, Psychiatria polska,
Copied contents to your clipboard!