[Effects of soybean isoflavone on reproductive development in SD rats]. 2012

Zhaoyan Liu, and Yanli Lv, and Yong Xue, and Defu Ma, and Xianglong Shao, and Guowei Li, and Yang Wang, and Qinghai Sheng, and Yumei Zhang, and Peiyu Wang
School of Public Health, Peking University, Beijing 100191, China.

OBJECTIVE To assess the effects of soybean isoflavone on reproductive development in SD rats. METHODS Forty 4 week-old SD rats (20 males and 20 females) were randomly divided into a control group and a soy isoflavone (SI) group according to their body mass, and were fed with normal diet or normal diet added with soy isoflavone (100 mg/kg BW), respectively. The body weight, daily food intake, estrous cycle, fertility index, pregnant index, gestation length, number of pups, blood hormone level, the weight of reproduction organ and the quality of sperm of the parental generation and the sex ratio, anogenital distance, vagina opening time, prepuce separation time of F1 generation were recorded. The data were analyzed by two independent t test, and the data of pups in each litter were analyzed as a unit. RESULTS Compared with the control group, the body weight and food utilization of male and female rats in SI group were lower before copulation (P < 0.05). The total number of sperm of parental males was higher (P < 0.05). Serum luteinizing hormone (LH) level of parental male was lower (P < 0.05), serum luteinizing hormone (LH), prolactin (PRL) and progesterone (P) of parental female were lower in SI group (P < 0.05). There were no significant differences of other indices such as estrous cycle, mating index, fertility index between two groups. CONCLUSIONS SI has certain effect on the bodyweight of parental males, food utilization of females, and the total number of sperm and the level of some hormones.

UI MeSH Term Description Entries
D007529 Isoflavones 3-Phenylchromones. Isomeric form of FLAVONOIDS in which the benzene group is attached to the 3 position of the benzopyran ring instead of the 2 position. 3-Benzylchroman-4-One,3-Benzylidene-4-Chromanone,Homoisoflavone,Homoisoflavones,Isoflavone,Isoflavone Derivative,3-Benzylchroman-4-Ones,3-Benzylidene-4-Chromanones,Isoflavone Derivatives,3 Benzylchroman 4 One,3 Benzylchroman 4 Ones,3 Benzylidene 4 Chromanone,3 Benzylidene 4 Chromanones,Derivative, Isoflavone,Derivatives, Isoflavone
D007986 Luteinizing Hormone A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity. ICSH (Interstitial Cell Stimulating Hormone),Interstitial Cell-Stimulating Hormone,LH (Luteinizing Hormone),Lutropin,Luteoziman,Luteozyman,Hormone, Interstitial Cell-Stimulating,Hormone, Luteinizing,Interstitial Cell Stimulating Hormone
D008297 Male Males
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011297 Prenatal Exposure Delayed Effects The consequences of exposing the FETUS in utero to certain factors, such as NUTRITION PHYSIOLOGICAL PHENOMENA; PHYSIOLOGICAL STRESS; DRUGS; RADIATION; and other physical or chemical factors. These consequences are observed later in the offspring after BIRTH. Delayed Effects, Prenatal Exposure,Late Effects, Prenatal Exposure
D011374 Progesterone The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS. Pregnenedione,Progesterone, (13 alpha,17 alpha)-(+-)-Isomer,Progesterone, (17 alpha)-Isomer,Progesterone, (9 beta,10 alpha)-Isomer
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013025 Glycine max An annual legume. The SEEDS of this plant are edible and used to produce a variety of SOY FOODS. Soy Beans,Soybeans,Bean, Soy,Beans, Soy,Soy Bean,Soybean
D013094 Spermatozoa Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility. Sperm,Spermatozoon,X-Bearing Sperm,X-Chromosome-Bearing Sperm,Y-Bearing Sperm,Y-Chromosome-Bearing Sperm,Sperm, X-Bearing,Sperm, X-Chromosome-Bearing,Sperm, Y-Bearing,Sperm, Y-Chromosome-Bearing,Sperms, X-Bearing,Sperms, X-Chromosome-Bearing,Sperms, Y-Bearing,Sperms, Y-Chromosome-Bearing,X Bearing Sperm,X Chromosome Bearing Sperm,X-Bearing Sperms,X-Chromosome-Bearing Sperms,Y Bearing Sperm,Y Chromosome Bearing Sperm,Y-Bearing Sperms,Y-Chromosome-Bearing Sperms

Related Publications

Zhaoyan Liu, and Yanli Lv, and Yong Xue, and Defu Ma, and Xianglong Shao, and Guowei Li, and Yang Wang, and Qinghai Sheng, and Yumei Zhang, and Peiyu Wang
January 2023, Frontiers in nutrition,
Zhaoyan Liu, and Yanli Lv, and Yong Xue, and Defu Ma, and Xianglong Shao, and Guowei Li, and Yang Wang, and Qinghai Sheng, and Yumei Zhang, and Peiyu Wang
June 2008, Biomedical and environmental sciences : BES,
Zhaoyan Liu, and Yanli Lv, and Yong Xue, and Defu Ma, and Xianglong Shao, and Guowei Li, and Yang Wang, and Qinghai Sheng, and Yumei Zhang, and Peiyu Wang
April 2011, Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine],
Zhaoyan Liu, and Yanli Lv, and Yong Xue, and Defu Ma, and Xianglong Shao, and Guowei Li, and Yang Wang, and Qinghai Sheng, and Yumei Zhang, and Peiyu Wang
May 2005, Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition,
Zhaoyan Liu, and Yanli Lv, and Yong Xue, and Defu Ma, and Xianglong Shao, and Guowei Li, and Yang Wang, and Qinghai Sheng, and Yumei Zhang, and Peiyu Wang
April 2019, Animal reproduction science,
Zhaoyan Liu, and Yanli Lv, and Yong Xue, and Defu Ma, and Xianglong Shao, and Guowei Li, and Yang Wang, and Qinghai Sheng, and Yumei Zhang, and Peiyu Wang
July 2005, Wei sheng yan jiu = Journal of hygiene research,
Zhaoyan Liu, and Yanli Lv, and Yong Xue, and Defu Ma, and Xianglong Shao, and Guowei Li, and Yang Wang, and Qinghai Sheng, and Yumei Zhang, and Peiyu Wang
August 2003, Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University,
Zhaoyan Liu, and Yanli Lv, and Yong Xue, and Defu Ma, and Xianglong Shao, and Guowei Li, and Yang Wang, and Qinghai Sheng, and Yumei Zhang, and Peiyu Wang
December 2010, Animal reproduction science,
Zhaoyan Liu, and Yanli Lv, and Yong Xue, and Defu Ma, and Xianglong Shao, and Guowei Li, and Yang Wang, and Qinghai Sheng, and Yumei Zhang, and Peiyu Wang
July 2007, Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine],
Zhaoyan Liu, and Yanli Lv, and Yong Xue, and Defu Ma, and Xianglong Shao, and Guowei Li, and Yang Wang, and Qinghai Sheng, and Yumei Zhang, and Peiyu Wang
April 2003, Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition,
Copied contents to your clipboard!