Biomaterial Database

Sclerosing cellular blue nevus simulating melanoma. 2012

Ikbal Esen Aydingoz, and Emel Dikicioglu-Cetin

Department of Dermatology, Acibadem University, School of Medicine, Istanbul, Turkey.

Sclerosing blue nevus is an uncommon variant of common blue nevus and shows an amorphous blue appearance at the edges with a hypopigmented center. Herein we present a 48-year-old female with sclerosing cellular blue nevus with extraordinary clinical and dermoscopic features simulating melanoma. The association of a whitish scarlike area with a pigmented dot pattern prominent throughout the lesion was unusual for a sclerosing cellular blue nevus. Besides pattern asymmetry, polychromasia and linear irregular vessels increased the mimicry. This case illustrates the importance of surgical excision and histopathological examination.

UI	MeSH Term	Description	Entries
D008545	Melanoma	A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)	Malignant Melanoma,Malignant Melanomas,Melanoma, Malignant,Melanomas,Melanomas, Malignant
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012598	Sclerosis	A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.	Scleroses
D012878	Skin Neoplasms	Tumors or cancer of the SKIN.	Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm
D018329	Nevus, Blue	Usually a benign tumor, that commonly presents as a solitary blue nodule with spindled MELANOCYTES covered by smooth SKIN. Several variants have been identified, one variant being malignant. The blue color is caused by large, densely packed melanocytes deep in the DERMIS of the nevus. In CHILDREN, they usually occur on the BUTTOCKS and LUMBOSACRAL REGION and are referred to as cellular blue nevi. Malignant blue nevi are more commonly found on the SCALP.	Blue Nevus,Cellular Blue Nevus,Blue Nevi,Blue Nevus, Cellular,Cellular Blue Nevi,Blue Nevi, Cellular,Nevi, Blue,Nevi, Cellular Blue,Nevus, Cellular Blue