-transparent.png){kind=logo}
The methyltrienolone binding protein (MTBP) found in human placental cytosol was found to require a low molecular weight modulator for steroid binding activity. Purification and characterization of the modulating activity showed that NAD+ is the endogenous substance responsible for activating MTBP to a form capable of steroid binding. The hierarchy of potency of exogenously added nucleotides is NADH greater than NAD+ = NADPH = NADP+. An investigation of the tissue distribution of human MTBP demonstrated that MTBP binding activity was present in placenta and chorion but absent from amnion and umbilical cord. Preliminary studies showed that rat, mouse, and rabbit placenta do not contain MTBP and suggest that MTBP may be a species-specific protein.
J O Macaulay, and
G L Warne, and
A I Smith, and
Z S Krozowski
August 2009,
EcoSal Plus,
J O Macaulay, and
G L Warne, and
A I Smith, and
Z S Krozowski
June 2021,
Angewandte Chemie (International ed. in English),
J O Macaulay, and
G L Warne, and
A I Smith, and
Z S Krozowski
May 1973,
Archives of biochemistry and biophysics,
J O Macaulay, and
G L Warne, and
A I Smith, and
Z S Krozowski
November 1966,
Archives internationales de physiologie et de biochimie,
J O Macaulay, and
G L Warne, and
A I Smith, and
Z S Krozowski
November 1993,
Archives of biochemistry and biophysics,
J O Macaulay, and
G L Warne, and
A I Smith, and
Z S Krozowski
November 1962,
Plant physiology,
J O Macaulay, and
G L Warne, and
A I Smith, and
Z S Krozowski
September 1974,
Infection and immunity,
J O Macaulay, and
G L Warne, and
A I Smith, and
Z S Krozowski
September 1968,
Journal of the American Chemical Society,
J O Macaulay, and
G L Warne, and
A I Smith, and
Z S Krozowski
May 1968,
The Biochemical journal,
J O Macaulay, and
G L Warne, and
A I Smith, and
Z S Krozowski
April 1980,
Biochimica et biophysica acta,
