Biomaterial Database

Effect of intraocular lens optic design on posterior capsular opacification. 1990

C P Born, and D K Ryan

Gundersen Clinic, Department of Ophthalmology, La Crosse, Wisconsin 54601.

Secondary capsular opacification is a common complication of extracapsular cataract extraction. We have done a retrospective study of 1,040 consecutive posterior chamber implants using four optic designs. The annual incidence of capsular opacification requiring capsulotomy was calculated to see if the optic design was a possible factor. The laser ridge and laser "peg" optics each had a cumulative capsulotomy rate of over 40.0% at three years and the convex-plano optic, over 40.0% at five years. Optics of plano-convex/biconvex designs had a cumulative capsulotomy rate of 5.0% at three years and 6.5% at five years. These results strongly suggest that capsular opacification is retarded when there is broad adhesion of the lens optic to the posterior capsule.

UI	MeSH Term	Description	Entries
D007903	Lens Capsule, Crystalline	The thin noncellular outer covering of the CRYSTALLINE LENS composed mainly of COLLAGEN TYPE IV and GLYCOSAMINOGLYCANS. It is secreted by the embryonic anterior and posterior epithelium. The embryonic posterior epithelium later disappears.	Capsule, Crystalline Lens,Capsules, Crystalline Lens,Crystalline Lens Capsule,Crystalline Lens Capsules,Lens Capsules, Crystalline
D007905	Lens Diseases	Diseases involving the CRYSTALLINE LENS.	Disease, Lens,Diseases, Lens,Lens Disease
D007908	Lens, Crystalline	A transparent, biconvex structure of the EYE, enclosed in a capsule and situated behind the IRIS and in front of the vitreous humor (VITREOUS BODY). It is slightly overlapped at its margin by the ciliary processes. Adaptation by the CILIARY BODY is crucial for OCULAR ACCOMMODATION.	Eye Lens,Lens, Eye,Crystalline Lens
D007910	Lenses, Intraocular	Artificial implanted lenses.	Implantable Contact Lens,Lens, Intraocular,Contact Lens, Implantable,Intraocular Lens,Intraocular Lenses,Lens, Implantable Contact
D008297	Male		Males
D011474	Prosthesis Design	The plan and delineation of prostheses in general or a specific prosthesis.	Design, Prosthesis,Designs, Prosthesis,Prosthesis Designs
D005260	Female		Females
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly