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In order to estimate the possible neurotoxicity of spinal analgesia with bupivacaine (Marcain), a total of ten patients were examined neurologically prior to spinal analgesia and seven days afterwards with somatosensory evoked potentials (SEP) and biotesiometry. The objective neurological examination results and SEP were entirely unchanged. At control examination with biotesiometry, altered vibration sense bilaterally over the medial malleoli was found in one patient but not on the pulp of the great toe bilaterally. Alterations in vibration in this patient were within the intraindividual variation as described by Fagius & Wahren. The method of examination employed here has not previously been employed systematically for follow-up investigation or elucidation of neurological deficits following spinal analgesia.
T W Jespersen, and
H J Hansen, and
K J Christensen
January 1975,
International anesthesiology clinics,
T W Jespersen, and
H J Hansen, and
K J Christensen
March 1989,
Minerva anestesiologica,
T W Jespersen, and
H J Hansen, and
K J Christensen
May 1998,
Canadian journal of anaesthesia = Journal canadien d'anesthesie,
T W Jespersen, and
H J Hansen, and
K J Christensen
February 1988,
Lancet (London, England),
T W Jespersen, and
H J Hansen, and
K J Christensen
April 1987,
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society,
T W Jespersen, and
H J Hansen, and
K J Christensen
June 1988,
Muscle & nerve,
T W Jespersen, and
H J Hansen, and
K J Christensen
January 1989,
Neurologie et psychiatrie,
T W Jespersen, and
H J Hansen, and
K J Christensen
October 1982,
Journal of neurosurgery,
T W Jespersen, and
H J Hansen, and
K J Christensen
January 1984,
Annals of neurology,
T W Jespersen, and
H J Hansen, and
K J Christensen
October 1984,
Surgical neurology,
