Asymptomatic stenoses of carotid arteries. 2012

I M Ignat'ev

The study was aimed at determining the prevalence of carotid artery stenoses while carrying out a screening population examination and at specifying the indications for endarterectomy in symptom-free patients. We carried out a screening examination by means of duplex scanning of 624 people (495 men and 129 women) aged over 50 years old and having no transient or persistent neurological symptoms or a history of an endured ischaemic stroke. The patients' average age amounted to 58.8±8.7 years. The examined patients were subdivided into two groups. Group One was composed of 485 patients presenting with various risk factors for the development of stroke: arterial hypertension, CAD, diabetes mellitus, hereditary predisposition. Group Two consisted of 139 subjects with no evident manifesting signs of cardiovascular diseases. The frequency of revealing ICA stenoses > 50% in the group comprising patients with risk factors (14.8%) was significantly higher (p = 0.002) than that (4.5%) in the group of apparently healthy people. From 2009 to 2011 the operation of carotid endarterectomy (CEA) was performed in 89 (15.9% of the total number of CEA) patients with asymptomatic stenoses of carotid arteries (ASCA), ICA stenting was performed in 15 patients. CEA in patients with asymptomatic lesions was carried out in ICA stenoses from 70 to 99%, and in a series of patients with unstable and ulcerated plaques with a high degree of embolization according to the findings of TCDG in stenoses from 60% and more. There were neither strokes nor lethal outcomes after the operations. Also given is a brief review of the literature covering contemporary problems concerning ASCA.

UI MeSH Term Description Entries
D008297 Male Males
D008403 Mass Screening Organized periodic procedures performed on large groups of people for the purpose of detecting disease. Screening,Mass Screenings,Screening, Mass,Screenings,Screenings, Mass
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D002339 Carotid Arteries Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery. Arteries, Carotid,Artery, Carotid,Carotid Artery
D002545 Brain Ischemia Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION. Cerebral Ischemia,Ischemic Encephalopathy,Encephalopathy, Ischemic,Ischemia, Cerebral,Brain Ischemias,Cerebral Ischemias,Ischemia, Brain,Ischemias, Cerebral,Ischemic Encephalopathies
D003627 Data Interpretation, Statistical Application of statistical procedures to analyze specific observed or assumed facts from a particular study. Data Analysis, Statistical,Data Interpretations, Statistical,Interpretation, Statistical Data,Statistical Data Analysis,Statistical Data Interpretation,Analyses, Statistical Data,Analysis, Statistical Data,Data Analyses, Statistical,Interpretations, Statistical Data,Statistical Data Analyses,Statistical Data Interpretations
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

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