-transparent.png){kind=logo}
We developed a new method to detect human T cell leukemia virus type I (HTLV-I) provirus by amplifying the pX region of the HTLV-I genome by means of the polymerase chain reaction (PCR) method. This new method was used to examine babies delivered by HTLV-I carrier women for HTLV-I vertical transmission. It was found that intra-uterine infection with HTLV-I can occur, though rarely, and some babies carry HTLV-I provirus despite their negative response to HTLV-I antibody, and, noticeably, some of the babies found negative by the conventional antigen detection method may be positive when tested by the PCR method. It was also confirmed with the PCR method that the incidence of vertical transmission of HTLV-I can be reduced to about 1/5 by replacing breast feeding with bottle feeding and frozen mother's milk feeding. It was also found that vertical transmission of HTLV-I can occur at high incidence rates even when the duration of breast feeding is 3 months or less.
S Saito, and
Y Ando, and
K Furuki, and
T Tanigawa, and
K Kakimoto, and
I Moriyama, and
M Ichijo
January 1991,
Journal of acquired immune deficiency syndromes,
S Saito, and
Y Ando, and
K Furuki, and
T Tanigawa, and
K Kakimoto, and
I Moriyama, and
M Ichijo
February 1993,
Japanese journal of cancer research : Gann,
S Saito, and
Y Ando, and
K Furuki, and
T Tanigawa, and
K Kakimoto, and
I Moriyama, and
M Ichijo
January 1990,
Disease markers,
S Saito, and
Y Ando, and
K Furuki, and
T Tanigawa, and
K Kakimoto, and
I Moriyama, and
M Ichijo
November 1991,
Leukemia,
S Saito, and
Y Ando, and
K Furuki, and
T Tanigawa, and
K Kakimoto, and
I Moriyama, and
M Ichijo
November 1990,
Nihon rinsho. Japanese journal of clinical medicine,
S Saito, and
Y Ando, and
K Furuki, and
T Tanigawa, and
K Kakimoto, and
I Moriyama, and
M Ichijo
January 1990,
Soins. Gynecologie, obstetrique, puericulture, pediatrie,
S Saito, and
Y Ando, and
K Furuki, and
T Tanigawa, and
K Kakimoto, and
I Moriyama, and
M Ichijo
December 1993,
Acta medica Okayama,
S Saito, and
Y Ando, and
K Furuki, and
T Tanigawa, and
K Kakimoto, and
I Moriyama, and
M Ichijo
March 1991,
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology,
S Saito, and
Y Ando, and
K Furuki, and
T Tanigawa, and
K Kakimoto, and
I Moriyama, and
M Ichijo
December 2011,
Jornal da Sociedade Brasileira de Fonoaudiologia,
S Saito, and
Y Ando, and
K Furuki, and
T Tanigawa, and
K Kakimoto, and
I Moriyama, and
M Ichijo
January 1995,
JAMA,
