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Development of gadolinium based nanoparticles having an affinity towards melanin. 2013
Jessica Morlieras, and
Jean-Michel Chezal, and
Elisabeth Miot-Noirault, and
Amandine Roux, and
Laurence Heinrich-Balard, and
Richard Cohen, and
Sébastien Tarrit, and
Charles Truillet, and
Anna Mignot, and
Roxanne Hachani, and
David Kryza, and
Rodolphe Antoine, and
Philippe Dugourd, and
Pascal Perriat, and
Marc Janier, and
Lucie Sancey, and
François Lux, and
Olivier Tillement
Laboratoire de Physico-Chimie des Matériaux Luminescents, UMR 5620 CNRS - Université Claude Bernard Lyon 1, Université de Lyon, 69622 Villeurbanne Cedex, France.
Small Rigid Platforms (SRPs) are sub-5 nanometre gadolinium based nanoparticles that have been developed for multimodal imaging and theranostic applications. They are composed of a polysiloxane network surrounded by gadolinium chelates. A covalent coupling with quinoxaline derivatives has been performed. Such derivatives have proven their affinity for melanin frequently expressed in primary melanoma cases. Three different quinoxaline derivatives have been synthesised and coupled to the nanoparticles. The affinity of the grafted nanoparticles for melanin has then been shown in vitro by surface plasmon resonance on a homemade melanin grafted gold chip.
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Amandine Roux, and
Laurence Heinrich-Balard, and
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Sébastien Tarrit, and
Charles Truillet, and
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Roxanne Hachani, and
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Rodolphe Antoine, and
Philippe Dugourd, and
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Elisabeth Miot-Noirault, and
Amandine Roux, and
Laurence Heinrich-Balard, and
Richard Cohen, and
Sébastien Tarrit, and
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Rodolphe Antoine, and
Philippe Dugourd, and
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Acta pharmacologica et toxicologica,
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Jean-Michel Chezal, and
Elisabeth Miot-Noirault, and
Amandine Roux, and
Laurence Heinrich-Balard, and
Richard Cohen, and
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Rodolphe Antoine, and
Philippe Dugourd, and
Pascal Perriat, and
Marc Janier, and
Lucie Sancey, and
François Lux, and
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Upsala journal of medical sciences,
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Elisabeth Miot-Noirault, and
Amandine Roux, and
Laurence Heinrich-Balard, and
Richard Cohen, and
Sébastien Tarrit, and
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Rodolphe Antoine, and
Philippe Dugourd, and
Pascal Perriat, and
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ACS nano,
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Amandine Roux, and
Laurence Heinrich-Balard, and
Richard Cohen, and
Sébastien Tarrit, and
Charles Truillet, and
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Rodolphe Antoine, and
Philippe Dugourd, and
Pascal Perriat, and
Marc Janier, and
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Rodolphe Antoine, and
Philippe Dugourd, and
Pascal Perriat, and
Marc Janier, and
Lucie Sancey, and
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Materials science & engineering. C, Materials for biological applications,
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Laurence Heinrich-Balard, and
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Nanomedicine (London, England),
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Amandine Roux, and
Laurence Heinrich-Balard, and
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Philippe Dugourd, and
Pascal Perriat, and
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Laurence Heinrich-Balard, and
Richard Cohen, and
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David Kryza, and
Rodolphe Antoine, and
Philippe Dugourd, and
Pascal Perriat, and
Marc Janier, and
Lucie Sancey, and
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Elisabeth Miot-Noirault, and
Amandine Roux, and
Laurence Heinrich-Balard, and
Richard Cohen, and
Sébastien Tarrit, and
Charles Truillet, and
Anna Mignot, and
Roxanne Hachani, and
David Kryza, and
Rodolphe Antoine, and
Philippe Dugourd, and
Pascal Perriat, and
Marc Janier, and
Lucie Sancey, and
François Lux, and
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Journal of neuroradiology = Journal de neuroradiologie,
