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Changing the way we do business: recommendations to accelerate biomarker development in pancreatic cancer. 2013
Margaret A Tempero, and
David Klimstra, and
Jordan Berlin, and
Tony Hollingsworth, and
Paula Kim, and
Nipun Merchant, and
Malcolm Moore, and
Doug Pleskow, and
Andrea Wang-Gillam, and
Andrew M Lowy
Pancreas Center, University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94115, USA. mtempero@medicine.ucsf.edu
Pancreatic ductal adenocarcinoma is the most aggressive of all epithelial malignancies. In contrast to the favorable trends seen in most other common malignancies, the five-year survival of patients with this disease remains only 6%, a statistic that has changed minimally for decades. Only two drugs have been approved by the U.S. Food and Drug Administration (FDA) for use in pancreatic cancer in the last 15 years, and there are no established strategies for early detection.
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