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Thyrotropin receptor antibody assays: clinical utility. 2013

William E Winter, and Ishwarlal Jialal, and Sridevi Devaraj

UI MeSH Term Description Entries
D008297 Male Males
D005260 Female Females
D006111 Graves Disease A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy). Basedow's Disease,Exophthalmic Goiter,Goiter, Exophthalmic,Graves' Disease,Basedow Disease,Hyperthyroidism, Autoimmune,Basedows Disease,Disease, Basedow,Disease, Basedow's,Disease, Graves,Disease, Graves',Exophthalmic Goiters,Goiters, Exophthalmic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001681 Biological Assay A method of measuring the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. It includes virulence studies in animal fetuses in utero, mouse convulsion bioassay of insulin, quantitation of tumor-initiator systems in mouse skin, calculation of potentiating effects of a hormonal factor in an isolated strip of contracting stomach muscle, etc. Bioassay,Assay, Biological,Assays, Biological,Biologic Assay,Biologic Assays,Assay, Biologic,Assays, Biologic,Bioassays,Biological Assays
D018828 Immunoglobulins, Thyroid-Stimulating Autoantibodies that bind to the thyroid-stimulating hormone (TSH) receptor (RECEPTORS, THYROTROPIN) on thyroid epithelial cells. The autoantibodies mimic TSH causing an unregulated production of thyroid hormones characteristic of GRAVES DISEASE. Antibodies, Thyroid-Stimulating,Ig Thyroid Stimulating,Thyroid-Stimulating Antibodies,Thyroid-Stimulating Autoantibodies,Thyroid-Stimulating Autoantibody,Thyroid-Stimulating Immunoglobulins,Immunoglobulin, Thyroid-Stimulating,Thyroid Stimulating Antibody,Thyroid-Stimulating Immunoglobulin,Antibody, Thyroid Stimulating,Autoantibody, Thyroid-Stimulating,Immunoglobulin, Thyroid Stimulating,Stimulating Antibody, Thyroid,Thyroid Stimulating Antibodies,Thyroid Stimulating Autoantibodies,Thyroid Stimulating Autoantibody,Thyroid Stimulating Immunoglobulin,Thyroid Stimulating Immunoglobulins,Thyroid Stimulating, Ig

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