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Apoconalbumin binds Mn(II) at two sites with association constants of K1 = 7 (+/- 1) X 10(4) and K2 = 0.4 (+/- 0.25) X 10(4) M-1. The binding is tighter in the presence of excess bicarbonate resulting in K1 = 1.8 (+/- 0.2) X 10(5) and K2 = 3 (+/- 2) X 10(4) M-1. The electron paramagnetic resonance spectrum (at both 9 and 35 GHz) of Mn(II) bound at the tight site reveals a rhombic distortion (lambda = E/D approximately equal to 0.25-0.31) in the protein ligand environment of the mental ion. An evaluation of the 1/pT1p, paramagnetic contribution to the longitudinal relaxation rate of solvent protons with Mn(II)-, Mn(III)-, and Fe(III)-derivatives of conalbumin revealed that the mental ion in each site of conalbumin is accessible to one water molecule. For Mn(II)-conalbumin and Mn(III)-conalbumin species, inner coordination sphere protons are rapidly exchanging with the bulk solvent, while slow exchange conditions prevail for Fe(III)-conalbumin.
J J Villafranca, and
R P Pillai, and
R C Woodworth
September 2013,
Inorganic chemistry,
J J Villafranca, and
R P Pillai, and
R C Woodworth
October 1997,
Guang pu xue yu guang pu fen xi = Guang pu,
J J Villafranca, and
R P Pillai, and
R C Woodworth
January 2003,
Inorganic chemistry,
J J Villafranca, and
R P Pillai, and
R C Woodworth
December 1998,
Biological & pharmaceutical bulletin,
J J Villafranca, and
R P Pillai, and
R C Woodworth
November 2009,
Dalton transactions (Cambridge, England : 2003),
J J Villafranca, and
R P Pillai, and
R C Woodworth
January 2014,
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,
J J Villafranca, and
R P Pillai, and
R C Woodworth
January 1975,
Bioinorganic chemistry,
J J Villafranca, and
R P Pillai, and
R C Woodworth
July 2007,
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,
J J Villafranca, and
R P Pillai, and
R C Woodworth
August 2005,
Inorganic chemistry,
J J Villafranca, and
R P Pillai, and
R C Woodworth
July 1998,
Inorganic chemistry,
