-transparent.png){kind=logo}
Synthesis and biological evaluation of phosphonate analogues of nevirapine. 2013
Jay Parrish, and
Leah Tong, and
Michael Wang, and
Xiaowu Chen, and
Eric B Lansdon, and
Carina Cannizzaro, and
Xubin Zheng, and
Manoj C Desai, and
Lianhong Xu
Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, USA. Jay.Parrish@gilead.com
A series of nevirapine-based analogues containing the phosphonate functionality were prepared and evaluated in vitro against HIV RT. The effect of the phosphonate was evaluated against the wild type and Y181C HIV replication. An in vivo PK study was performed on a select analogue.
Related Publications
Jay Parrish, and
Leah Tong, and
Michael Wang, and
Xiaowu Chen, and
Eric B Lansdon, and
Carina Cannizzaro, and
Xubin Zheng, and
Manoj C Desai, and
Lianhong Xu
June 2000,
Archives of pharmacal research,
Jay Parrish, and
Leah Tong, and
Michael Wang, and
Xiaowu Chen, and
Eric B Lansdon, and
Carina Cannizzaro, and
Xubin Zheng, and
Manoj C Desai, and
Lianhong Xu
January 2001,
European journal of medicinal chemistry,
Jay Parrish, and
Leah Tong, and
Michael Wang, and
Xiaowu Chen, and
Eric B Lansdon, and
Carina Cannizzaro, and
Xubin Zheng, and
Manoj C Desai, and
Lianhong Xu
September 2011,
Carbohydrate research,
Jay Parrish, and
Leah Tong, and
Michael Wang, and
Xiaowu Chen, and
Eric B Lansdon, and
Carina Cannizzaro, and
Xubin Zheng, and
Manoj C Desai, and
Lianhong Xu
February 2004,
Bioorganic & medicinal chemistry letters,
Jay Parrish, and
Leah Tong, and
Michael Wang, and
Xiaowu Chen, and
Eric B Lansdon, and
Carina Cannizzaro, and
Xubin Zheng, and
Manoj C Desai, and
Lianhong Xu
April 2013,
Bioorganic & medicinal chemistry,
Jay Parrish, and
Leah Tong, and
Michael Wang, and
Xiaowu Chen, and
Eric B Lansdon, and
Carina Cannizzaro, and
Xubin Zheng, and
Manoj C Desai, and
Lianhong Xu
August 2003,
Bioorganic & medicinal chemistry letters,
Jay Parrish, and
Leah Tong, and
Michael Wang, and
Xiaowu Chen, and
Eric B Lansdon, and
Carina Cannizzaro, and
Xubin Zheng, and
Manoj C Desai, and
Lianhong Xu
September 2003,
Organic letters,
Jay Parrish, and
Leah Tong, and
Michael Wang, and
Xiaowu Chen, and
Eric B Lansdon, and
Carina Cannizzaro, and
Xubin Zheng, and
Manoj C Desai, and
Lianhong Xu
July 2006,
Organic letters,
Jay Parrish, and
Leah Tong, and
Michael Wang, and
Xiaowu Chen, and
Eric B Lansdon, and
Carina Cannizzaro, and
Xubin Zheng, and
Manoj C Desai, and
Lianhong Xu
August 2003,
Chemical communications (Cambridge, England),
Jay Parrish, and
Leah Tong, and
Michael Wang, and
Xiaowu Chen, and
Eric B Lansdon, and
Carina Cannizzaro, and
Xubin Zheng, and
Manoj C Desai, and
Lianhong Xu
November 2013,
Bioorganic & medicinal chemistry letters,
