BIOMAT Database Logo BIOMAT Database Logo

[Continuous infusion of epidural morphine to relieve postoperative pain. Protocol and results]. 1990

A M Yáñez González, and M A Camba Rodríguez, and M J Valle Ortiz, and A García Iglesias, and P González Guerra, and R Mosquera Freire, and R Pita Romero
Servicios de Anestesiología, de Traumatología y de Farmacia, Complejo Hospitalario Arquitecto Marcide-Novoa Santos, Ferrol.

We have evaluated the efficaciousness and side effects of continuous administration of morphine by lumbar epidural route for relieving postoperative pain in major surgery of the abdomen and orthopedic surgery. Lumbar epidural catheters were placed to 25 patients (mean age, 52 years) before induction of general anesthesia. All patients received a 4 mg bolus dose of morphine sulfate 1 hour before finalization of general anesthesia and subsequently they were placed on a continuous infusion of morphine sulfate at 0.3-1 mg/h. All patients achieved analgesia which maintained then pain-free and allowed early ambulation and initiation of active respiratory physiotherapy. Duration of continuous analgesia varied from 3 to 5 days. No patient presented respiratory depression; four presented nausea and eight had urinary retention. We believe that continuous epidural infusion of morphine is efficacious and safe for the treatment of acute postoperative pain in patients undergoing abdomen major surgery and orthopedic surgery.

UI MeSH Term Description Entries
D007263 Infusions, Parenteral The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping. Intra-Abdominal Infusions,Intraperitoneal Infusions,Parenteral Infusions,Peritoneal Infusions,Infusion, Intra-Abdominal,Infusion, Intraperitoneal,Infusion, Parenteral,Infusion, Peritoneal,Infusions, Intra-Abdominal,Infusions, Intraperitoneal,Infusions, Peritoneal,Intra Abdominal Infusions,Intra-Abdominal Infusion,Intraperitoneal Infusion,Parenteral Infusion,Peritoneal Infusion
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009020 Morphine The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle. Morphine Sulfate,Duramorph,MS Contin,Morphia,Morphine Chloride,Morphine Sulfate (2:1), Anhydrous,Morphine Sulfate (2:1), Pentahydrate,Oramorph SR,SDZ 202-250,SDZ202-250,Chloride, Morphine,Contin, MS,SDZ 202 250,SDZ 202250,SDZ202 250,SDZ202250,Sulfate, Morphine
D010149 Pain, Postoperative Pain during the period after surgery. Acute Post-operative Pain,Acute Postoperative Pain,Chronic Post-operative Pain,Chronic Post-surgical Pain,Chronic Postoperative Pain,Chronic Postsurgical Pain,Pain, Post-operative,Persistent Postsurgical Pain,Post-operative Pain,Post-operative Pain, Acute,Post-operative Pain, Chronic,Post-surgical Pain,Postoperative Pain, Acute,Postoperative Pain, Chronic,Postsurgical Pain,Postoperative Pain,Acute Post operative Pain,Chronic Post operative Pain,Chronic Post surgical Pain,Chronic Postsurgical Pains,Pain, Acute Post-operative,Pain, Acute Postoperative,Pain, Chronic Post-operative,Pain, Chronic Post-surgical,Pain, Chronic Postoperative,Pain, Chronic Postsurgical,Pain, Persistent Postsurgical,Pain, Post operative,Pain, Post-surgical,Pain, Postsurgical,Post operative Pain,Post operative Pain, Acute,Post operative Pain, Chronic,Post surgical Pain,Post-operative Pains,Post-surgical Pain, Chronic,Postsurgical Pain, Chronic,Postsurgical Pain, Persistent
D002985 Clinical Protocols Precise and detailed plans for the study of a medical or biomedical problem and/or plans for a regimen of therapy. Protocols, Clinical,Research Protocols, Clinical,Treatment Protocols,Clinical Protocol,Clinical Research Protocol,Clinical Research Protocols,Protocol, Clinical,Protocol, Clinical Research,Protocols, Clinical Research,Protocols, Treatment,Research Protocol, Clinical,Treatment Protocol
D004341 Drug Evaluation Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals. Evaluation Studies, Drug,Drug Evaluation Studies,Drug Evaluation Study,Drug Evaluations,Evaluation Study, Drug,Evaluation, Drug,Evaluations, Drug,Studies, Drug Evaluation,Study, Drug Evaluation
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

A M Yáñez González, and M A Camba Rodríguez, and M J Valle Ortiz, and A García Iglesias, and P González Guerra, and R Mosquera Freire, and R Pita Romero
[Continuous epidural infusion of 0.01% morphine for postoperative pain relief].
January 1988, Masui. The Japanese journal of anesthesiology,
A M Yáñez González, and M A Camba Rodríguez, and M J Valle Ortiz, and A García Iglesias, and P González Guerra, and R Mosquera Freire, and R Pita Romero
[Continuous epidural infusion of bupivacaine and morphine for postoperative pain relief].
February 1990, Masui. The Japanese journal of anesthesiology,
A M Yáñez González, and M A Camba Rodríguez, and M J Valle Ortiz, and A García Iglesias, and P González Guerra, and R Mosquera Freire, and R Pita Romero
Epidural morphine infusion. Continuous pain relief.
May 1984, AORN journal,
A M Yáñez González, and M A Camba Rodríguez, and M J Valle Ortiz, and A García Iglesias, and P González Guerra, and R Mosquera Freire, and R Pita Romero
Continuous-plus-on-demand epidural infusion of buprenorphine versus morphine in postoperative treatment of pain. Postoperative epidural infusion of buprenorphine.
March 1987, Arzneimittel-Forschung,
A M Yáñez González, and M A Camba Rodríguez, and M J Valle Ortiz, and A García Iglesias, and P González Guerra, and R Mosquera Freire, and R Pita Romero
Postoperative pain prevention by continuous epidural infusion.
February 1981, Anaesthesia,
A M Yáñez González, and M A Camba Rodríguez, and M J Valle Ortiz, and A García Iglesias, and P González Guerra, and R Mosquera Freire, and R Pita Romero
Failure of epidural morphine to relieve pain in labour.
February 1980, Anaesthesia,
A M Yáñez González, and M A Camba Rodríguez, and M J Valle Ortiz, and A García Iglesias, and P González Guerra, and R Mosquera Freire, and R Pita Romero
Continuous morphine infusion for postoperative pain in children.
January 1988, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
A M Yáñez González, and M A Camba Rodríguez, and M J Valle Ortiz, and A García Iglesias, and P González Guerra, and R Mosquera Freire, and R Pita Romero
Continuous morphine infusion for postoperative pain in children.
September 1987, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
A M Yáñez González, and M A Camba Rodríguez, and M J Valle Ortiz, and A García Iglesias, and P González Guerra, and R Mosquera Freire, and R Pita Romero
Comparison of continuous epidural infusion of morphine/bupivacaine with fentanyl/bupivacaine for postoperative pain relief.
May 1994, Acta anaesthesiologica Scandinavica,
A M Yáñez González, and M A Camba Rodríguez, and M J Valle Ortiz, and A García Iglesias, and P González Guerra, and R Mosquera Freire, and R Pita Romero
Comparison of continuous epidural infusion of fentanyl-bupivacaine and morphine-bupivacaine in management of postoperative pain.
June 1988, Anesthesia and analgesia,
Copied contents to your clipboard!