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[Treatment of chronic viral hepatitis: achievements and prospects]. 2012

E V Golovanova

The review focuses on the current state of the problem of chronic viral hepatitis (CVH),B and C. Presents an analysis of the effectiveness of schemes of antiviral therapy (AVT) of chronic HCV-infection and current understanding of the treatment tactics of patients with inadequate response to therapy. Particular attention is paid to the nearest perspectives in treatment of chronic hepatitis C (CH C). The questions of the effectiveness of AVT chronic HBV-infection, the results of the comparative effectiveness of interferon (IFN) and nucleoside analogs (AN) in the treatment of chronic hepatitis B (CH B) are observed in the article. Special attention is paid to the treatment of chronic viral infections at the stage of liver cirrhosis (LC).

UI MeSH Term Description Entries
D008103 Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. Cirrhosis, Liver,Fibrosis, Liver,Hepatic Cirrhosis,Liver Fibrosis,Cirrhosis, Hepatic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000998 Antiviral Agents Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. Antiviral,Antiviral Agent,Antiviral Drug,Antivirals,Antiviral Drugs,Agent, Antiviral,Agents, Antiviral,Drug, Antiviral,Drugs, Antiviral
D019694 Hepatitis B, Chronic INFLAMMATION of the LIVER in humans caused by HEPATITIS B VIRUS lasting six months or more. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact. Chronic Hepatitis B,Chronic Hepatitis B Virus Infection,Hepatitis B Virus Infection, Chronic
D019698 Hepatitis C, Chronic INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS. Chronic Hepatitis C

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