BIOMAT Database Logo BIOMAT Database Logo

[Sinonasal carcinoma and exposure to wood and leather dust: analysis of 36 cases]. 2012

M Bracci, and L Mariotti, and S Staffolani, and E Strafella, and C Carlucci, and E Pasquini, and P Tarchini, and M Re, and L Santarelli
Medicina del Lavoro, Dipartimento di Scienze Cliniche e Molecolari, Facoltà di Medicina e Chirurgia, Università Politecnica delle Marche, Ancona, Italy. m.bracci@univpm.it

In order to define the best strategies of prevention and diagnosis of sinonasal cancer, the aim of our study was the investigation of the etiological and prognostic factors related to 36 cases. The enrolled cases were composed mostly of men working in the footwear industry, with a mean age of 63.7 years and mean exposure of 34.6 years. The period between the start of exposure and the appearance of the neoplasm was of 44.6 years, the time between the onset of symptoms and diagnosis was of 10.8 months. Our results suggest that a diagnosis within 6 months after the onset of symptoms is associated with a lower tumor stage, a better survival and to a lower rate of recurrence. Nasal obstruction (58.3%) and epistaxis (52.7%) are the main initial symptoms. In order to obtain an early diagnosis, in addition to periodic clinical controls, a proper information of workers is required.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009784 Occupational Diseases Diseases caused by factors involved in one's employment. Diseases, Occupational,Occupational Illnesses,Disease, Occupational,Illnesse, Occupational,Illnesses, Occupational,Occupational Disease,Occupational Illnesse
D010255 Paranasal Sinus Neoplasms Tumors or cancer of the PARANASAL SINUSES. Cancer of Paranasal Sinus,Neoplasms, Paranasal Sinus,Paranasal Sinus Cancer,Cancer, Paranasal Sinus,Cancers, Paranasal Sinus,Neoplasm, Paranasal Sinus,Paranasal Sinus Cancers,Paranasal Sinus Neoplasm
D002277 Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for "cancer." Carcinoma, Anaplastic,Carcinoma, Spindle-Cell,Carcinoma, Undifferentiated,Carcinomatosis,Epithelial Neoplasms, Malignant,Epithelioma,Epithelial Tumors, Malignant,Malignant Epithelial Neoplasms,Neoplasms, Malignant Epithelial,Anaplastic Carcinoma,Anaplastic Carcinomas,Carcinoma, Spindle Cell,Carcinomas,Carcinomatoses,Epithelial Neoplasm, Malignant,Epithelial Tumor, Malignant,Epitheliomas,Malignant Epithelial Neoplasm,Malignant Epithelial Tumor,Malignant Epithelial Tumors,Neoplasm, Malignant Epithelial,Spindle-Cell Carcinoma,Spindle-Cell Carcinomas,Tumor, Malignant Epithelial,Undifferentiated Carcinoma,Undifferentiated Carcinomas
D004391 Dust Earth or other matter in fine, dry particles. (Random House Unabridged Dictionary, 2d ed) House Dust,Housedust,Dust, House
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014934 Wood A product of hard secondary xylem composed of CELLULOSE, hemicellulose, and LIGNANS, that is under the bark of trees and shrubs. It is used in construction and as a source of CHARCOAL and many other products. Woods
D016273 Occupational Exposure The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation. Exposure, Occupational,Exposures, Occupational,Occupational Exposures

Related Publications

M Bracci, and L Mariotti, and S Staffolani, and E Strafella, and C Carlucci, and E Pasquini, and P Tarchini, and M Re, and L Santarelli
Wood-related occupations, wood dust exposure, and sinonasal cancer.
October 1986, American journal of epidemiology,
M Bracci, and L Mariotti, and S Staffolani, and E Strafella, and C Carlucci, and E Pasquini, and P Tarchini, and M Re, and L Santarelli
K-ras mutations in sinonasal adenocarcinomas in patients occupationally exposed to wood or leather dust.
April 1998, Cancer letters,
M Bracci, and L Mariotti, and S Staffolani, and E Strafella, and C Carlucci, and E Pasquini, and P Tarchini, and M Re, and L Santarelli
Genome-wide somatic mutation analysis of sinonasal adenocarcinoma with and without wood dust exposure.
May 2024, Genes and environment : the official journal of the Japanese Environmental Mutagen Society,
M Bracci, and L Mariotti, and S Staffolani, and E Strafella, and C Carlucci, and E Pasquini, and P Tarchini, and M Re, and L Santarelli
K-ras mutations in sinonasal cancers in relation to wood dust exposure.
February 2008, BMC cancer,
M Bracci, and L Mariotti, and S Staffolani, and E Strafella, and C Carlucci, and E Pasquini, and P Tarchini, and M Re, and L Santarelli
[Laryngeal carcinoma caused by exposure to wood dust?].
June 1995, Laryngo- rhino- otologie,
M Bracci, and L Mariotti, and S Staffolani, and E Strafella, and C Carlucci, and E Pasquini, and P Tarchini, and M Re, and L Santarelli
Wood dust exposure and risks of nasopharyngeal carcinoma: a meta-analysis.
August 2020, European journal of public health,
M Bracci, and L Mariotti, and S Staffolani, and E Strafella, and C Carlucci, and E Pasquini, and P Tarchini, and M Re, and L Santarelli
Occupational Exposure to Wood Dust and the Burden of Nasopharynx and Sinonasal Cancer in Canada.
January 2022, International journal of environmental research and public health,
M Bracci, and L Mariotti, and S Staffolani, and E Strafella, and C Carlucci, and E Pasquini, and P Tarchini, and M Re, and L Santarelli
Sinonasal cancer and wood dust exposure: results from a case-control study.
August 1994, American journal of epidemiology,
M Bracci, and L Mariotti, and S Staffolani, and E Strafella, and C Carlucci, and E Pasquini, and P Tarchini, and M Re, and L Santarelli
Occupational exposure to formaldehyde and wood dust and nasopharyngeal carcinoma.
June 2000, Occupational and environmental medicine,
M Bracci, and L Mariotti, and S Staffolani, and E Strafella, and C Carlucci, and E Pasquini, and P Tarchini, and M Re, and L Santarelli
[Nasal sinus carcinoma after wood dust exposure. Morphological spectrum of 100 cases].
February 2004, Der Pathologe,
Copied contents to your clipboard!