Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia.
Crush Syndromes,Syndrome, Crush,Syndromes, Crush
D004630
Emergencies
Situations or conditions requiring immediate intervention to avoid serious adverse results.
Emergency
D005392
First Aid
Emergency care or treatment given to a person who suddenly becomes ill or injured before full medical services become available.
Aid, First,Aids, First,First Aids
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012771
Shock, Hemorrhagic
Acute hemorrhage or excessive fluid loss resulting in HYPOVOLEMIA.
Hemorrhagic Shock
D012774
Shock, Traumatic
Shock produced as a result of trauma.
Traumatic Shock
D014115
Toxemia
A condition produced by the presence of toxins or other harmful substances in the BLOOD.