BIOMAT Database Logo BIOMAT Database Logo

Comparison of (18)F-FDG PET/CT and (68)Ga-DOTATATE PET/CT imaging in metastasized Merkel cell carcinoma. 2013

Maximilian Epstude, and Katharina Tornquist, and Christian Riklin, and Francesca di Lenardo, and Ralph Winterhalder, and Urs Hug, and Klaus Strobel
Departments of Nuclear Medicine and Radiology, Cantonal Hospital Lucerne, Lucerne, Switzerland.

Merkel cell carcinoma (MCC) is a rare but very aggressive neuroendocrine tumor of the skin in elderly patients with higher mortality compared with melanoma. No evidence-based standardized chemotherapy exists for metastasized patients.We report the case of an 87-year-old patient with the history of resection of a large MCC of the parietal scalp planned for radiotherapy and staged with FDG PET/CT showing disseminated distant metastases. Ga-DOTATATE PET/CT revealed more extensive tumor load compared with FDG, and due to the intensive expression of somatostatin receptors the patient qualified for Y DOTATOC therapy.

UI MeSH Term Description Entries
D009362 Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. Metastase,Metastasis,Metastases, Neoplasm,Metastasis, Neoplasm,Neoplasm Metastases,Metastases
D009942 Organometallic Compounds A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed) Metallo-Organic Compound,Metallo-Organic Compounds,Metalloorganic Compound,Organometallic Compound,Metalloorganic Compounds,Compound, Metallo-Organic,Compound, Metalloorganic,Compound, Organometallic,Compounds, Metallo-Organic,Compounds, Metalloorganic,Compounds, Organometallic,Metallo Organic Compound,Metallo Organic Compounds
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old
D012878 Skin Neoplasms Tumors or cancer of the SKIN. Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm
D014057 Tomography, X-Ray Computed Tomography using x-ray transmission and a computer algorithm to reconstruct the image. CAT Scan, X-Ray,CT Scan, X-Ray,Cine-CT,Computerized Tomography, X-Ray,Electron Beam Computed Tomography,Tomodensitometry,Tomography, Transmission Computed,X-Ray Tomography, Computed,CAT Scan, X Ray,CT X Ray,Computed Tomography, X-Ray,Computed X Ray Tomography,Computerized Tomography, X Ray,Electron Beam Tomography,Tomography, X Ray Computed,Tomography, X-Ray Computer Assisted,Tomography, X-Ray Computerized,Tomography, X-Ray Computerized Axial,Tomography, Xray Computed,X Ray Computerized Tomography,X Ray Tomography, Computed,X-Ray Computer Assisted Tomography,X-Ray Computerized Axial Tomography,Beam Tomography, Electron,CAT Scans, X-Ray,CT Scan, X Ray,CT Scans, X-Ray,CT X Rays,Cine CT,Computed Tomography, Transmission,Computed Tomography, X Ray,Computed Tomography, Xray,Computed X-Ray Tomography,Scan, X-Ray CAT,Scan, X-Ray CT,Scans, X-Ray CAT,Scans, X-Ray CT,Tomographies, Computed X-Ray,Tomography, Computed X-Ray,Tomography, Electron Beam,Tomography, X Ray Computer Assisted,Tomography, X Ray Computerized,Tomography, X Ray Computerized Axial,Transmission Computed Tomography,X Ray Computer Assisted Tomography,X Ray Computerized Axial Tomography,X Ray, CT,X Rays, CT,X-Ray CAT Scan,X-Ray CAT Scans,X-Ray CT Scan,X-Ray CT Scans,X-Ray Computed Tomography,X-Ray Computerized Tomography,Xray Computed Tomography
D015266 Carcinoma, Merkel Cell A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245) Merkel Cell Tumor,Merkel Cell Cancer,Merkel Cell Carcinoma,Merkle Tumors,Cancer, Merkel Cell,Cell Cancer, Merkel,Tumor, Merkel Cell,Tumors, Merkle
D049268 Positron-Emission Tomography An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower. PET Imaging,PET Scan,Positron-Emission Tomography Imaging,Tomography, Positron-Emission,Imaging, PET,Imaging, Positron-Emission Tomography,PET Imagings,PET Scans,Positron Emission Tomography,Positron Emission Tomography Imaging,Positron-Emission Tomography Imagings,Scan, PET,Tomography Imaging, Positron-Emission,Tomography, Positron Emission
D019788 Fluorodeoxyglucose F18 The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162) 18F Fluorodeoxyglucose,18FDG,2-Fluoro-2-deoxy-D-glucose,2-Fluoro-2-deoxyglucose,Fludeoxyglucose F 18,18F-FDG,Fluorine-18-fluorodeoxyglucose,Fluorodeoxyglucose F 18,2 Fluoro 2 deoxy D glucose,2 Fluoro 2 deoxyglucose,F 18, Fludeoxyglucose,F 18, Fluorodeoxyglucose,F18, Fluorodeoxyglucose,Fluorine 18 fluorodeoxyglucose,Fluorodeoxyglucose, 18F
D064847 Multimodal Imaging The use of combination of imaging techniques or platforms (e.g., MRI SCAN and PET SCAN) encompassing aspects of anatomical, functional, or molecular imaging methods. Hybrid Imaging,Imaging, Hybrid,Imaging, Multimodal

Related Publications

Maximilian Epstude, and Katharina Tornquist, and Christian Riklin, and Francesca di Lenardo, and Ralph Winterhalder, and Urs Hug, and Klaus Strobel
Comparison of 68 Ga-DOTATATE PET/CT and 68 Ga-Pentixiafor PET/CT Imaging in a Case of Merkel Cell Carcinoma.
April 2023, Clinical nuclear medicine,
Maximilian Epstude, and Katharina Tornquist, and Christian Riklin, and Francesca di Lenardo, and Ralph Winterhalder, and Urs Hug, and Klaus Strobel
Comparison of 18 F-FDG PET/CT and 68 Ga-DOTATATE PET/CT in the Targeted Imaging of Culprit Tumors Causing Osteomalacia.
May 2021, Orthopaedic surgery,
Maximilian Epstude, and Katharina Tornquist, and Christian Riklin, and Francesca di Lenardo, and Ralph Winterhalder, and Urs Hug, and Klaus Strobel
Comparison of maximum likelihood and conventional PET scatter scaling methods for 18 F-FDG and 68 Ga-DOTATATE PET/CT.
August 2021, Medical physics,
Maximilian Epstude, and Katharina Tornquist, and Christian Riklin, and Francesca di Lenardo, and Ralph Winterhalder, and Urs Hug, and Klaus Strobel
(68)Ga-DOTATATE and (18)F-FDG PET/CT in Paraganglioma and Pheochromocytoma: utility, patterns and heterogeneity.
August 2016, Cancer imaging : the official publication of the International Cancer Imaging Society,
Maximilian Epstude, and Katharina Tornquist, and Christian Riklin, and Francesca di Lenardo, and Ralph Winterhalder, and Urs Hug, and Klaus Strobel
Targeting post-infarct inflammation by PET imaging: comparison of (68)Ga-citrate and (68)Ga-DOTATATE with (18)F-FDG in a mouse model.
February 2015, European journal of nuclear medicine and molecular imaging,
Maximilian Epstude, and Katharina Tornquist, and Christian Riklin, and Francesca di Lenardo, and Ralph Winterhalder, and Urs Hug, and Klaus Strobel
Comparison of 68 Ga-FAPI and 18 F-FDG PET/CT inmetastasis of thyroid papillary carcinoma.
January 2021, Hellenic journal of nuclear medicine,
Maximilian Epstude, and Katharina Tornquist, and Christian Riklin, and Francesca di Lenardo, and Ralph Winterhalder, and Urs Hug, and Klaus Strobel
Comparison of 68 Ga-FAPI and 18 F-FDG PET/CT in Finger Hidradenocarcinoma.
March 2023, Clinical nuclear medicine,
Maximilian Epstude, and Katharina Tornquist, and Christian Riklin, and Francesca di Lenardo, and Ralph Winterhalder, and Urs Hug, and Klaus Strobel
Comparison of 18 F-MFBG and 68 Ga-DOTATATE PET/CT in the Imaging of Metastatic Paraganglioma and Pheochromocytoma.
December 2022, Clinical nuclear medicine,
Maximilian Epstude, and Katharina Tornquist, and Christian Riklin, and Francesca di Lenardo, and Ralph Winterhalder, and Urs Hug, and Klaus Strobel
Superiority of 18 F-FDG PET/CT to 68 GA-FAPI PET/CT in Adrenocortical Tumor Imaging.
June 2023, Clinical nuclear medicine,
Maximilian Epstude, and Katharina Tornquist, and Christian Riklin, and Francesca di Lenardo, and Ralph Winterhalder, and Urs Hug, and Klaus Strobel
Comparison of (68)Ga-DOTATATE and (18)F-fluorodeoxyglucose PET/CT in the detection of recurrent medullary thyroid carcinoma.
January 2010, European journal of nuclear medicine and molecular imaging,
Copied contents to your clipboard!