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Successful immunotherapy in life-threatening parvovirus B19 infection in a child. 2013
Marine Butin, and
Yahia Mekki, and
Alice Phan, and
Geneviève Billaud, and
Sylvie Di Filippo, and
Etienne Javouhey, and
Pierre Cochat, and
Alexandre Belot
Service de Néphrologie, Dermatologie et Rhumatologie Pédiatrique, HFME, Hôpital Louis Pradel, Bron, France.
We report a case of an immunocompetent child who developed parvovirus B19 infection complicated by autoinflammatory disease with myocarditis, tamponade and macrophage activation syndrome. He recovered with immunotherapy including prednisone, immunoglobulins, cyclosporin and anakinra (anti-interleukin-1). The report shows that parvovirus can provoke severe systemic inflammation with acute heart injury and that anti-interleukin-1 might be considered in such parvovirus-related inflammation.
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