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OBJECTIVE To analyze caries activity of nasopharyngeal carcinoma (NPC) patients before and after radiation therapy. The study was also designed to analyze calcium and phosphorus concentrations in saliva of NPC patients before and after radiotherapy. METHODS Twenty-eight NPC patients and 20 healthy controls were included in this study. Resazurin disc method was used to detect caries activity of NPC patients before and after 70 Gy radiotherapy. The atomic absorption spectrometry and molybdenum-stibium antispetrophotography method were used to analyze calcium and phosphorus concentrations in saliva of NPC patients before and after 70 Gy radiotherapy and the healthy controls. RESULTS The results of resazurin disc method showed caries activity of NPC patients was increased after radiotherapy (P < 0.01). Calcium concentration in saliva of NPC patients before radiotherapy was (63.19 +/- 3.27) mg x L(-1), phosphorus concentration was (132.96 +/- 5.13) mg x L(-1). After 70 Gy radiotherapy, calcium concentration was (33.38 +/- 0.32) mg x L(-1), phosphorus concentration was (49.18 +/- 2.66) mg x L(-1). The difference of calcium and phosphorus concentrations in saliva before and after radiotherapy was significant (P < 0.01). CONCLUSIONS Caries activities of NPC patients increase after radiotherapy. Calcium and phosphorus concentrations in saliva decrease after radiation therapy.
He Liu, and
Guoying Que, and
Li Zou
February 2001,
Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology,
He Liu, and
Guoying Que, and
Li Zou
February 1988,
Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology,
He Liu, and
Guoying Que, and
Li Zou
February 1996,
The Journal of laryngology and otology,
He Liu, and
Guoying Que, and
Li Zou
March 1979,
Pediatric dentistry,
He Liu, and
Guoying Que, and
Li Zou
October 1998,
Journal of clinical and experimental neuropsychology,
He Liu, and
Guoying Que, and
Li Zou
May 2023,
Bulletin du cancer,
He Liu, and
Guoying Que, and
Li Zou
September 2002,
Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology,
He Liu, and
Guoying Que, and
Li Zou
January 1954,
Acta medica Academiae Scientiarum Hungaricae,
He Liu, and
Guoying Que, and
Li Zou
May 2011,
Zhonghua zhong liu za zhi [Chinese journal of oncology],
He Liu, and
Guoying Que, and
Li Zou
June 2005,
Ai zheng = Aizheng = Chinese journal of cancer,
