Biomaterial Database

[Portal hypertension of extrahepatic origin]. 1990

D Valla

Service d'hépato-gastroentérologie, groupe hospitalier Pitié-Salpêtrière, Paris.

Portal hypertension may be due to a suprahepatic or infrahepatic block. Suprahepatic blocks result in Budd-Chiari syndrome. Their principal cause is myeloproliferative syndromes and invasion of the hepatic veins by a tumour. Their main manifestations are ascites and liver enlargement. Treatment consists of re-establishing the hepatofugal drainage. Infrahepatic blocks are due to obstruction of the portal vein, either by thrombosis facilitated by thrombogenic diseases, or by a tumour. Their main consequences are gastrointestinal hemorrhages. Treatment consists of preventing the rupture of oesophageal varices.

UI	MeSH Term	Description	Entries
D006975	Hypertension, Portal	Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.	Cruveilhier-Baumgarten Disease,Cruveilhier-Baumgarten Syndrome,Cruveilhier Baumgarten Disease,Cruveilhier Baumgarten Syndrome,Disease, Cruveilhier-Baumgarten,Portal Hypertension,Portal Hypertensions,Syndrome, Cruveilhier-Baumgarten
D011169	Portal Vein	A short thick vein formed by union of the superior mesenteric vein and the splenic vein.	Portal Veins,Vein, Portal,Veins, Portal
D006502	Budd-Chiari Syndrome	A condition in which the hepatic venous outflow is obstructed anywhere from the small HEPATIC VEINS to the junction of the INFERIOR VENA CAVA and the RIGHT ATRIUM. Usually the blockage is extrahepatic and caused by blood clots (THROMBUS) or fibrous webs. Parenchymal FIBROSIS is uncommon.	Chiari's Syndrome,Hepatic Venous Outflow Obstruction,Hepatic Vein Thrombosis,Budd Chiari Syndrome,Chiari Syndrome,Chiaris Syndrome,Hepatic Vein Thromboses,Thromboses, Hepatic Vein,Thrombosis, Hepatic Vein,Vein Thromboses, Hepatic,Vein Thrombosis, Hepatic
D006503	Hepatic Veins	Veins which drain the liver.	Hepatic Vein,Vein, Hepatic,Veins, Hepatic
D006504	Hepatic Veno-Occlusive Disease	Liver disease that is caused by injuries to the ENDOTHELIAL CELLS of the vessels and subendothelial EDEMA, but not by THROMBOSIS. Extracellular matrix, rich in FIBRONECTINS, is usually deposited around the HEPATIC VEINS leading to venous outflow occlusion and sinusoidal obstruction.	Sinusoidal Obstruction Syndrome,Veno-Occlusive Disease, Hepatic,Hepatic Veno Occlusive Disease,Disease, Hepatic Veno-Occlusive,Hepatic Veno-Occlusive Diseases,Syndrome, Sinusoidal Obstruction,Veno Occlusive Disease, Hepatic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man