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Gamma-Glutamyltranspeptidase activity of patients having an ascitic cirrhosis due to ethanol consumption is high (139 mU/ml) when the patient is still drinking at the time of the assay; it is lower when the patient had stopped drinking at least two months before the assay (49 mU/ml). On the other hand, in 10 patients out of the 11 who submitted to a second assay gamma-glutamyltranspeptidase decreases as soon as the patient abstains from alcohol. In 4 abstinent patients re-examined one year after the first measurement, the gamma-glutamyltranspeptidase activity had decreased to the reference values of Szasz. The half time of the return to normal has been estimated by extrapolation from the ethylic model at between 11 and 54 days. We conclude that the hyper gamma-glutamyltranspeptidase in cirrhotics is due to the ethanol impregnation and that repeated assays of the enzyme show whether the patient abstains from alcohol or not.
J Lamy, and
M C Baglin, and
E Aron, and
J Weill
February 1973,
Wiener klinische Wochenschrift,
J Lamy, and
M C Baglin, and
E Aron, and
J Weill
April 1981,
Lancet (London, England),
J Lamy, and
M C Baglin, and
E Aron, and
J Weill
March 1981,
Lancet (London, England),
J Lamy, and
M C Baglin, and
E Aron, and
J Weill
July 1975,
Sbornik lekarsky,
J Lamy, and
M C Baglin, and
E Aron, and
J Weill
April 1974,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
J Lamy, and
M C Baglin, and
E Aron, and
J Weill
March 1973,
DTW. Deutsche tierarztliche Wochenschrift,
J Lamy, and
M C Baglin, and
E Aron, and
J Weill
July 1980,
Clinica chimica acta; international journal of clinical chemistry,
J Lamy, and
M C Baglin, and
E Aron, and
J Weill
September 1968,
Vnitrni lekarstvi,
J Lamy, and
M C Baglin, and
E Aron, and
J Weill
September 1968,
Ceskoslovenska gastroenterologie a vyziva,
J Lamy, and
M C Baglin, and
E Aron, and
J Weill
May 1975,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
