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Epidemiological and clinical complexity of amoxicillin-clavulanate-resistant Escherichia coli. 2013
Jesús Rodríguez-Baño, and
Jesús Oteo, and
Adriana Ortega, and
Macarena Villar, and
M Carmen Conejo, and
Germán Bou, and
Maitane Aranzamendi-Zaldumbide, and
Emilia Cercenado, and
Mercè Gurguí, and
Luis Martínez-Martínez, and
María Merino, and
Alba Rivera, and
Antonio Oliver, and
Irene Weber, and
Alvaro Pascual, and
Rosa M Bartolomé, and
Juan José Gónzalez-López, and
José Campos
Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario Virgen Macarena, Seville, Spain. jesusrb@us.es
Two hundred twelve patients with colonization/infection due to amoxicillin-clavulanate (AMC)-resistant Escherichia coli were studied. OXA-1- and inhibitor-resistant TEM (IRT)-producing strains were associated with urinary tract infections, while OXA-1 producers and chromosomal AmpC hyperproducers were associated with bacteremic infections. AMC resistance in E. coli is a complex phenomenon with heterogeneous clinical implications.
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