Changes of choroidal thickness, intraocular pressure and other optical coherence tomographic parameters after haemodialysis. 2013

Sung Jae Yang, and Yang Hee Han, and Gyoung Il Song, and Chung Hyun Lee, and Sae Woon Sohn
Department of Ophthalmology, Gangneung Asan Hospital, University of Ulsan, College of Medicine, Gangwon, South Korea. sungjaeyang@gmail.com

BACKGROUND The aim was to evaluate changes in choroidal thickness, intraocular pressure (IOP) and other parameters of optical coherence tomography, such as central foveal thickness (CFT), macular volume, peripapillary retinal nerve fibre layer (RNFL) thickness after haemodialysis (HD). METHODS Thirty-four eyes of 34 chronic renal failure patients (9 eyes with diabetic patients) who underwent haemodialysis in the Dialysis Unit of Gangneung Asan Hospital were included. CFT, macular volume, peripapillary RNFL and choroidal thickness were measured before and after haemodialysis by optical coherence tomography (OCT, Spectralis; Heidelberg Engineering). Changes in the IOP were evaluated with Goldmann applanation tonometry before and after haemodialysis. RESULTS The average choroidal thickness decreased significantly, from 233.1 ± 77.5 μm to 219.1 ± 76.8 μm (paired t-test, p < 0.001). This change correlated with the amount of body weight lost (Pearson's correlation coefficient = 0.348, p = 0.044). The mean IOP decreased from 15.1 ± 2.6 mmHg to 13.9 ± 2.2 mmHg after haemodialysis (paired t-test, p = 0.03). The change in macular volume and the small decrease in CFT (214.0 ± 21.0 μm to 213.8 ± 21.8 μm) were not significant. The measured overall change in RNFL thickness from 93.6 ± 15.5 μm to 94.7 ± 14.6 μm was not significant. CONCLUSIONS Haemodialysis can affect various ocular parameters, particularly choroidal thickness and IOP.

UI MeSH Term Description Entries
D007429 Intraocular Pressure The pressure of the fluids in the eye. Ocular Tension,Intraocular Pressures,Ocular Tensions,Pressure, Intraocular,Pressures, Intraocular,Tension, Ocular,Tensions, Ocular
D007676 Kidney Failure, Chronic The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION. ESRD,End-Stage Renal Disease,Renal Disease, End-Stage,Renal Failure, Chronic,Renal Failure, End-Stage,Chronic Kidney Failure,End-Stage Kidney Disease,Chronic Renal Failure,Disease, End-Stage Kidney,Disease, End-Stage Renal,End Stage Kidney Disease,End Stage Renal Disease,End-Stage Renal Failure,Kidney Disease, End-Stage,Renal Disease, End Stage,Renal Failure, End Stage
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009412 Nerve Fibers Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM. Cerebellar Mossy Fibers,Mossy Fibers, Cerebellar,Cerebellar Mossy Fiber,Mossy Fiber, Cerebellar,Nerve Fiber
D002829 Choroid The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA. Choriocapillaris,Haller Layer,Haller's Layer,Sattler Layer,Sattler's Layer,Choroids
D003430 Cross-Sectional Studies Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time. Disease Frequency Surveys,Prevalence Studies,Analysis, Cross-Sectional,Cross Sectional Analysis,Cross-Sectional Survey,Surveys, Disease Frequency,Analyses, Cross Sectional,Analyses, Cross-Sectional,Analysis, Cross Sectional,Cross Sectional Analyses,Cross Sectional Studies,Cross Sectional Survey,Cross-Sectional Analyses,Cross-Sectional Analysis,Cross-Sectional Study,Cross-Sectional Surveys,Disease Frequency Survey,Prevalence Study,Studies, Cross-Sectional,Studies, Prevalence,Study, Cross-Sectional,Study, Prevalence,Survey, Cross-Sectional,Survey, Disease Frequency,Surveys, Cross-Sectional
D003930 Diabetic Retinopathy Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION. Diabetic Retinopathies,Retinopathies, Diabetic,Retinopathy, Diabetic
D005260 Female Females
D005584 Fovea Centralis An area approximately 1.5 millimeters in diameter within the macula lutea where the retina thins out greatly because of the oblique shifting of all layers except the pigment epithelium layer. It includes the sloping walls of the fovea (clivus) and contains a few rods in its periphery. In its center (foveola) are the cones most adapted to yield high visual acuity, each cone being connected to only one ganglion cell. (Cline et al., Dictionary of Visual Science, 4th ed)

Related Publications

Sung Jae Yang, and Yang Hee Han, and Gyoung Il Song, and Chung Hyun Lee, and Sae Woon Sohn
February 2014, The British journal of ophthalmology,
Sung Jae Yang, and Yang Hee Han, and Gyoung Il Song, and Chung Hyun Lee, and Sae Woon Sohn
November 2012, Japanese journal of ophthalmology,
Sung Jae Yang, and Yang Hee Han, and Gyoung Il Song, and Chung Hyun Lee, and Sae Woon Sohn
September 2016, Acta ophthalmologica,
Sung Jae Yang, and Yang Hee Han, and Gyoung Il Song, and Chung Hyun Lee, and Sae Woon Sohn
June 2017, Acta ophthalmologica,
Sung Jae Yang, and Yang Hee Han, and Gyoung Il Song, and Chung Hyun Lee, and Sae Woon Sohn
August 2021, Scientific reports,
Sung Jae Yang, and Yang Hee Han, and Gyoung Il Song, and Chung Hyun Lee, and Sae Woon Sohn
January 2013, Clinical ophthalmology (Auckland, N.Z.),
Sung Jae Yang, and Yang Hee Han, and Gyoung Il Song, and Chung Hyun Lee, and Sae Woon Sohn
May 2015, Indian journal of ophthalmology,
Sung Jae Yang, and Yang Hee Han, and Gyoung Il Song, and Chung Hyun Lee, and Sae Woon Sohn
January 2015, Journal of Ayub Medical College, Abbottabad : JAMC,
Sung Jae Yang, and Yang Hee Han, and Gyoung Il Song, and Chung Hyun Lee, and Sae Woon Sohn
January 2018, Ophthalmic research,
Sung Jae Yang, and Yang Hee Han, and Gyoung Il Song, and Chung Hyun Lee, and Sae Woon Sohn
April 2018, Scientific reports,
Copied contents to your clipboard!