BIOMAT Database Logo BIOMAT Database Logo

Cuticle specific antigens from filarial parasite Setaria digitata. 1990

J J Bright, and R Kaleysaraj
Department of Biochemistry, University of Kerala, Trivandrum, India.

A fairly clean antigenic cuticle was isolated from the S. digitata by dissection. Crossed immunoelectrophoresis of cuticular antigens against rabbit antiserum to cuticular antigens gave 30 anodic and 5 cathodic precipitin arcs. The cuticle antiserum cross reacted with muscle, uterus and pseudocoelomic fluid. When the antiserum was absorbed individually with these cross reacting somatic preparations, analysis against cuticle antigens gave only a limited number of precipitin arcs. But the results are clear enough to indicate the presence of cuticle specific antigens. As the cuticle of the parasite is in contact with the host system, an antigenic preparation from it may prove a useful tool for the detection of filariasis.

UI MeSH Term Description Entries
D007122 Immunoelectrophoresis A technique that combines protein electrophoresis and double immunodiffusion. In this procedure proteins are first separated by gel electrophoresis (usually agarose), then made visible by immunodiffusion of specific antibodies. A distinct elliptical precipitin arc results for each protein detectable by the antisera.
D005370 Filarioidea A superfamily of nematodes of the order SPIRURIDA. Members possess a filiform body and a mouth surrounded by papillae. Litomosoides,Filarioideas,Litomosoide
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000947 Antigens, Helminth Any part or derivative of a helminth that elicits an immune reaction. The most commonly seen helminth antigens are those of the schistosomes. Helminth Antigens
D012719 Setariasis Infection with nematodes of the genus Setaria. This condition is usually seen in cattle and equines and is of little pathogenic significance, although migration of the worm to the eye may lead to blindness. Setariases

Related Publications

J J Bright, and R Kaleysaraj
Excretory secretory antigens of filarial parasite Setaria digitata.
March 1990, Indian journal of experimental biology,
J J Bright, and R Kaleysaraj
Fumarate reductase system of filarial parasite Setaria digitata.
April 1992, Biochemical and biophysical research communications,
J J Bright, and R Kaleysaraj
Molecular characterisation of a hsp70 gene from the filarial parasite Setaria digitata.
April 1999, International journal for parasitology,
J J Bright, and R Kaleysaraj
Oxidative activities in mitochondria-like particles from Setaria digitata, a filarial parasite.
December 1988, The Biochemical journal,
J J Bright, and R Kaleysaraj
Biosynthesis of isoprenoid compounds in cattle filarial parasite Setaria digitata.
November 1994, Biochemical and biophysical research communications,
J J Bright, and R Kaleysaraj
Quinone mediated ATP production in the filarial parasite Setaria digitata.
March 1990, Biochemical and biophysical research communications,
J J Bright, and R Kaleysaraj
Quinone mediated electron transport system in the filarial parasite Setaria digitata.
January 1991, Biochemical and biophysical research communications,
J J Bright, and R Kaleysaraj
Succinate oxidase and fumarate reductase systems of filarial parasite Setaria digitata.
April 2000, Indian journal of biochemistry & biophysics,
J J Bright, and R Kaleysaraj
Isolation and analysis of surface antigens of filarial nematode Setaria digitata.
August 1991, Indian journal of experimental biology,
J J Bright, and R Kaleysaraj
Antigenic analysis of purified surface antigens of filarial nematode Setaria digitata.
May 1992, Indian journal of experimental biology,
Copied contents to your clipboard!