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The capacity of S. aureus peptidoglycan (PG) for inducing the luminol-dependent chemiluminescence of human lymphocytes has been studied. Lymphocytes taken from adult donors have been found to give dose-dependent reaction to S. aureus PG, while lymphocytes from newborn infants have been inert under the same conditions. Essential differences in the kinetics of response to PG (the maximum intensity of chemiluminescence occurs in 25-30 minutes) and to phytohemagglutinin (the maximum intensity is reached in 1 minute) were observed. These results are considered as the manifestation of specific sensitization to bacterial peptidoglycans, which may be rapidly detected by reactive chemiluminescence.
A N Maianskiĭ, and
S P RVssanov, and
D G Astafĕv, and
O A Osipov
December 1991,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
A N Maianskiĭ, and
S P RVssanov, and
D G Astafĕv, and
O A Osipov
September 1991,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
A N Maianskiĭ, and
S P RVssanov, and
D G Astafĕv, and
O A Osipov
January 1980,
International archives of allergy and applied immunology,
A N Maianskiĭ, and
S P RVssanov, and
D G Astafĕv, and
O A Osipov
February 2016,
Biochimie,
A N Maianskiĭ, and
S P RVssanov, and
D G Astafĕv, and
O A Osipov
July 1975,
Zeitschrift fur Immunitatsforschung, experimentelle und klinische Immunologie,
A N Maianskiĭ, and
S P RVssanov, and
D G Astafĕv, and
O A Osipov
December 2012,
Applied microbiology and biotechnology,
A N Maianskiĭ, and
S P RVssanov, and
D G Astafĕv, and
O A Osipov
January 1990,
Microbiology and immunology,
A N Maianskiĭ, and
S P RVssanov, and
D G Astafĕv, and
O A Osipov
December 1984,
Infection and immunity,
A N Maianskiĭ, and
S P RVssanov, and
D G Astafĕv, and
O A Osipov
December 1978,
Acta pathologica et microbiologica Scandinavica. Section B, Microbiology,
A N Maianskiĭ, and
S P RVssanov, and
D G Astafĕv, and
O A Osipov
June 2010,
Nature communications,
