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[Aluminum osteopathy]. 1990

C Povýsil, and I Sotorník, and A Válek
II. patologicko-anatomický ústav FVL KU, Praha.

Histochemical study of 155 bone biopsies from dialyzed patients revealed 43 cases with aluminium deposits in bone trabeculae localized along the mineralization line or in phagolysosomes of bone marrow macrophages. Aluminium was limited to macrophages in 5 cases, to mineralization line in 23 cases, and found in both localities in 15 patients. Patients with a positive finding mostly had osteomalacia (8 times) which was combined in some cases (35 times) with mild fibrous osteodystrophy. Authors failed to prove histochemically positive deposits in dialyzed patients with serious parathyroidism. Simultaneous deposits of aluminium and hemosiderin were found in the mineralization line in three patients. Bone deposition of aluminium seems to influence somehow the bone lesion but precise interpretation of the phenomenon has not been given.

UI MeSH Term Description Entries
D010018 Osteomalacia Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis. Adult Rickets,Rickets, Adult
D001842 Bone and Bones A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX. Bone Tissue,Bone and Bone,Bone,Bones,Bones and Bone,Bones and Bone Tissue,Bony Apophyses,Bony Apophysis,Condyle,Apophyses, Bony,Apophysis, Bony,Bone Tissues,Condyles,Tissue, Bone,Tissues, Bone
D006435 Renal Dialysis Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION. Dialysis, Extracorporeal,Dialysis, Renal,Extracorporeal Dialysis,Hemodialysis,Dialyses, Extracorporeal,Dialyses, Renal,Extracorporeal Dialyses,Hemodialyses,Renal Dialyses
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000535 Aluminum A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98. Aluminium,Aluminium-27,Aluminum-27,Aluminium 27,Aluminum 27

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