-transparent.png){kind=logo}
Marrow fibroblast colony formation was studied in patients with myeloproliferative disorders, using human serum or platelet-derived growth factor plus plasma-derived serum as growth-stimulating factors. Colony numbers negatively correlated with the patient's age, but were not different from those of controls. However, both maximum and average cell numbers per colony were significantly increased in patients with chronic myelocytic leukemia (CML) as compared to controls. These results suggest that fibroblast colony-forming cells with high sensitivity to human serum mitogen(s) exist in a CML bone marrow. These may possibly be involved in one of the mechanism concerned with promoting fibrosis in this disease.
A Kimura, and
O Katoh, and
H Hyodo, and
S Kusumi, and
A Kuramoto
January 1982,
Terapevticheskii arkhiv,
A Kimura, and
O Katoh, and
H Hyodo, and
S Kusumi, and
A Kuramoto
October 1980,
The Tokai journal of experimental and clinical medicine,
A Kimura, and
O Katoh, and
H Hyodo, and
S Kusumi, and
A Kuramoto
July 1979,
Cancer research,
A Kimura, and
O Katoh, and
H Hyodo, and
S Kusumi, and
A Kuramoto
September 1984,
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society,
A Kimura, and
O Katoh, and
H Hyodo, and
S Kusumi, and
A Kuramoto
September 1988,
Cell and tissue kinetics,
A Kimura, and
O Katoh, and
H Hyodo, and
S Kusumi, and
A Kuramoto
February 1983,
The Tohoku journal of experimental medicine,
A Kimura, and
O Katoh, and
H Hyodo, and
S Kusumi, and
A Kuramoto
August 1977,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
A Kimura, and
O Katoh, and
H Hyodo, and
S Kusumi, and
A Kuramoto
March 1986,
Cancer genetics and cytogenetics,
A Kimura, and
O Katoh, and
H Hyodo, and
S Kusumi, and
A Kuramoto
March 1985,
Gematologiia i transfuziologiia,
A Kimura, and
O Katoh, and
H Hyodo, and
S Kusumi, and
A Kuramoto
November 1983,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
