Identification and quantification of furanocoumarins in stem bark and wood of eight Algerian varieties of Ficus carica by RP-HPLC-DAD and RP-HPLC-DAD-MS. 2013

Samia Rouaiguia-Bouakkaz, and Habiba Amira-Guebailia, and Céline Rivière, and Jean-Claude Delaunay, and Pierre Waffo-Téguo, and Jean-Michel Mérillon
Laboratoire de Chimie Appliquée, Université du 8 Mai 1945, Guelma 24000, Algérie.

Furanocoumarins are the major phytoalexins of Ficus carica and are effective natural drug candidates for treatment of several types of cancer and skin disease. The objectives of this study were to analyze and quantify linear furanocoumarins, mainly psoralen and bergapten, in wood and bark of stems from eight Algerian varieties of fig and to establish the differences in the content of these metabolites in the eight local samples. Psoralen and bergapten contents in the stem bark and wood (in microg/g DW) varied respectively from 146.6 to 1110.3 and from 395.7 to 1671.8 for psoralen, and from 114.3 to 524.0 and from 144.2 to 718.6 for bergapten. This study fills a gap in our knowledge of furanocoumarin distribution in different parts of the fig tree. Psoralen and bergapten concentrations were higher in the wood than in the stem bark. Most of the dark fruited fig trees produce these two coumarins more than the green ones.

UI MeSH Term Description Entries
D011564 Furocoumarins Polycyclic compounds consisting of a furan ring fused with coumarin. They commonly occur in PLANTS, especially UMBELLIFERAE and RUTACEAE, as well as PSORALEA. Furanocoumarin,Furanocoumarins,Furocoumarin,Psoralens,Angelicins
D002851 Chromatography, High Pressure Liquid Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed. Chromatography, High Performance Liquid,Chromatography, High Speed Liquid,Chromatography, Liquid, High Pressure,HPLC,High Performance Liquid Chromatography,High-Performance Liquid Chromatography,UPLC,Ultra Performance Liquid Chromatography,Chromatography, High-Performance Liquid,High-Performance Liquid Chromatographies,Liquid Chromatography, High-Performance
D000462 Algeria A country in northern Africa bordering the Mediterranean Sea, between MOROCCO and TUNISIA. Its capital is Algiers.
D018547 Plant Stems Parts of plants that usually grow vertically upwards towards the light and support the leaves, buds, and reproductive structures. (From Concise Dictionary of Biology, 1990) Plant Stem,Stem, Plant,Stems, Plant
D024301 Plant Bark The outer layer of the woody parts of plants. Bark, Plant,Bark, Tree,Tree Bark,Barks, Plant,Barks, Tree,Plant Barks,Tree Barks
D030681 Ficus A plant genus of the family MORACEAE. It is the source of the familiar fig fruit and the latex from this tree contains FICAIN. Figs,Rubberplant,Fig,Rubberplants

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