[The experimental allotransplantation of trachea in canine]. 1990

T Shirakusa, and H Ueda, and T Saito
Second Department of Surgery, School of Medicine, Fukuoka University, Japan.

Twelve dogs were used for the experiment of allograft of the trachea. Under general anesthesia, the cervical trachea in the donor was exposed and five or six segments of cartilage were excised, and then, these grafts were transplanted at the central portion of the cervical trachea in the recipient. For the effective vascularization, the omental pedicle was transplanted around the graft. The immunosuppressant was administered in 5 dogs. In the experimental results, 5 dogs were survived over 30 days and one dog is now alive over 9 months with good condition. Postoperative bronchofiberscopic observation demonstrated that the formation of granulation occurred one week after transplantation and the stenosis developed and exacerbated by infection. In the long survived dog the anastomotic stenosis disappeared and the color of the mucosa of the graft was same as the recipient's. It was considered that the blood supply at the anastomotic portion was the most important factor for the viability of allograft of the trachea.

UI MeSH Term Description Entries
D009852 Omentum A double-layered fold of peritoneum that attaches the STOMACH to other organs in the ABDOMINAL CAVITY. Omentums
D001999 Bronchoscopy Endoscopic examination, therapy or surgery of the bronchi. Bronchoscopic Surgical Procedures,Surgical Procedures, Bronchoscopic,Bronchoscopic Surgery,Surgery, Bronchoscopic,Bronchoscopic Surgeries,Bronchoscopic Surgical Procedure,Bronchoscopies,Surgeries, Bronchoscopic,Surgical Procedure, Bronchoscopic
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D006085 Graft Survival The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. Graft Survivals,Survival, Graft,Survivals, Graft
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013524 Surgical Flaps Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region. Island Flap,Island Flaps,Flap, Surgical,Flaps, Surgical,Pedicled Flap,Surgical Flap,Flap, Island,Flap, Pedicled,Flaps, Island,Flaps, Pedicled,Pedicled Flaps
D014132 Trachea The cartilaginous and membranous tube descending from the larynx and branching into the right and left main bronchi. Tracheas
D014184 Transplantation, Homologous Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals. Transplantation, Allogeneic,Allogeneic Grafting,Allogeneic Transplantation,Allografting,Homografting,Homologous Transplantation,Grafting, Allogeneic

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