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Backgrounds existing in the analytical signal always impair the effectiveness of signals and compromise selectivity and sensitivity of analytical methods. In order to perform further qualitative or quantitative analysis, the background should be corrected with a reasonable method. For this purpose, a new automatic method for background correction, which is based on morphological operations and weighted penalized least squares (MPLS), has been developed in this paper. It requires neither prior knowledge about the background nor an iteration procedure or manual selection of a suitable local minimum value. The method has been successfully applied to simulated datasets as well as experimental datasets from different instruments. The results show that the method is quite flexible and could handle different kinds of backgrounds. The proposed MPLS method is implemented and available as an open source package at http://code.google.com/p/mpls.
Zhong Li, and
De-Jian Zhan, and
Jia-Jun Wang, and
Jing Huang, and
Qing-Song Xu, and
Zhi-Min Zhang, and
Yi-Bao Zheng, and
Yi-Zeng Liang, and
Hong Wang
January 2018,
Journal of analytical methods in chemistry,
Zhong Li, and
De-Jian Zhan, and
Jia-Jun Wang, and
Jing Huang, and
Qing-Song Xu, and
Zhi-Min Zhang, and
Yi-Bao Zheng, and
Yi-Zeng Liang, and
Hong Wang
January 1994,
IEEE transactions on medical imaging,
Zhong Li, and
De-Jian Zhan, and
Jia-Jun Wang, and
Jing Huang, and
Qing-Song Xu, and
Zhi-Min Zhang, and
Yi-Bao Zheng, and
Yi-Zeng Liang, and
Hong Wang
November 2010,
Medical physics,
Zhong Li, and
De-Jian Zhan, and
Jia-Jun Wang, and
Jing Huang, and
Qing-Song Xu, and
Zhi-Min Zhang, and
Yi-Bao Zheng, and
Yi-Zeng Liang, and
Hong Wang
January 1993,
IEEE transactions on medical imaging,
Zhong Li, and
De-Jian Zhan, and
Jia-Jun Wang, and
Jing Huang, and
Qing-Song Xu, and
Zhi-Min Zhang, and
Yi-Bao Zheng, and
Yi-Zeng Liang, and
Hong Wang
December 2020,
Applied spectroscopy,
Zhong Li, and
De-Jian Zhan, and
Jia-Jun Wang, and
Jing Huang, and
Qing-Song Xu, and
Zhi-Min Zhang, and
Yi-Bao Zheng, and
Yi-Zeng Liang, and
Hong Wang
January 2015,
The Analyst,
Zhong Li, and
De-Jian Zhan, and
Jia-Jun Wang, and
Jing Huang, and
Qing-Song Xu, and
Zhi-Min Zhang, and
Yi-Bao Zheng, and
Yi-Zeng Liang, and
Hong Wang
May 2010,
The Analyst,
Zhong Li, and
De-Jian Zhan, and
Jia-Jun Wang, and
Jing Huang, and
Qing-Song Xu, and
Zhi-Min Zhang, and
Yi-Bao Zheng, and
Yi-Zeng Liang, and
Hong Wang
February 2021,
BMC bioinformatics,
Zhong Li, and
De-Jian Zhan, and
Jia-Jun Wang, and
Jing Huang, and
Qing-Song Xu, and
Zhi-Min Zhang, and
Yi-Bao Zheng, and
Yi-Zeng Liang, and
Hong Wang
November 2000,
IEEE transactions on medical imaging,
Zhong Li, and
De-Jian Zhan, and
Jia-Jun Wang, and
Jing Huang, and
Qing-Song Xu, and
Zhi-Min Zhang, and
Yi-Bao Zheng, and
Yi-Zeng Liang, and
Hong Wang
May 2019,
Applied optics,
