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A method to determine the P50 of whole blood is described using a modified American Optical reflectance oximeter, pump, and membrane tonometer, together with PO2, PCO2, and pH measurements in a standard blood gas machine. Determinations of P50 were made in 66 patients and normal subjects and in two situations where P50 was very low and very high. The results were compared to oxygen saturations calculated from measured oxygen content. The directly determined oxygen saturation agreed with the assumed saturation of 50 per cent in the oximeter within 0.5 per cent. The apparatus appears to be a simple and relatively inexpensive method to obtain P50 as long as blood carboxyhemoglobin or methemoglobin contents are not elevated.
B W Kirk, and
M B Raber, and
K R Duke
December 2011,
The Australian & New Zealand journal of obstetrics & gynaecology,
B W Kirk, and
M B Raber, and
K R Duke
May 1970,
Veterinariia,
B W Kirk, and
M B Raber, and
K R Duke
January 1987,
Laboratornoe delo,
B W Kirk, and
M B Raber, and
K R Duke
January 1947,
Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete,
B W Kirk, and
M B Raber, and
K R Duke
August 1972,
British medical journal,
B W Kirk, and
M B Raber, and
K R Duke
May 1954,
Science (New York, N.Y.),
B W Kirk, and
M B Raber, and
K R Duke
January 1952,
The Journal of laboratory and clinical medicine,
B W Kirk, and
M B Raber, and
K R Duke
January 1951,
Mikroskopie,
B W Kirk, and
M B Raber, and
K R Duke
January 1983,
Laboratornoe delo,
B W Kirk, and
M B Raber, and
K R Duke
November 1987,
Obstetrics and gynecology,
