-transparent.png){kind=logo}
The bone matrix of growing rats was labeled by multiple injections of 3H-proline, and demineralized bone matrix (DBM) was prepared. The DBM was allotransplanted heterotopically into growing rats. New bone formation was induced in and around the implants. The new bone formation was accompanied by a decrease in the content of 3H; 20 and 30 days after implantation, 72% and 46%, respectively, of the activity remained in the implants. Daily injections of indomethacin (2 mg/kg) inhibited calcium uptake by about 20% at 20 and 30 days and inhibited the release of 3H from the DBM to a similar degree. Heterotopic bone induction by DBM is accompanied by matrix resorption, and inhibition of the new bone formation decreases the resorption of DBM.
O S Nilsson, and
P E Persson, and
A Ekelund
July 1991,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
O S Nilsson, and
P E Persson, and
A Ekelund
March 1980,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
O S Nilsson, and
P E Persson, and
A Ekelund
January 1986,
Archives of orthopaedic and traumatic surgery. Archiv fur orthopadische und Unfall-Chirurgie,
O S Nilsson, and
P E Persson, and
A Ekelund
January 1982,
Clinical orthopaedics and related research,
O S Nilsson, and
P E Persson, and
A Ekelund
January 1996,
Ryoikibetsu shokogun shirizu,
O S Nilsson, and
P E Persson, and
A Ekelund
December 2002,
Current rheumatology reports,
O S Nilsson, and
P E Persson, and
A Ekelund
December 1984,
Clinical orthopaedics and related research,
O S Nilsson, and
P E Persson, and
A Ekelund
August 2006,
Clinical oral implants research,
O S Nilsson, and
P E Persson, and
A Ekelund
May 1973,
The Journal of clinical investigation,
O S Nilsson, and
P E Persson, and
A Ekelund
February 2014,
Journal of molecular medicine (Berlin, Germany),
