Biomaterial Database

[Alveolar recruitment maneuvers oxygenation effects in newborns with infant respiratory distress syndrome]. 2013

U S Aleksandrovich, and O A Pechueva, and K V Pshenisnov

Infant respiratory distress syndrome (IRDS) is a most common neonatal critical condition which is accompanied by the hypoxemia increase and needs the use of the highly invasive respiratory support methods. Alveolar recruitment maneuver is a one of the most promising and pathogenetically grounded method. The method is widely used in adults. but its use in Pediatric patients requires evidence of the effectiveness. OBJECTIVE To study alveolar recruitment maneuver use effectiveness in newborns with IRDS by the examining patient's clinical status and the nearest and long-term outcomes. METHODS Alveolar recruitment maneuver was used in 45 newborns with IRDS accompanied by the hypoxemia (group 1). Retrospective analysis of conditions and outcomes in 19 newborns with IRDS, without use of alveolar recruitment maneuver, was conducted in 2009 (group 2). RESULTS Alveolar recruitment maneuver improves ventilation and oxygenation in newborns with IRDS (paO2 53 torr in group 1 vs. 36 torr in group 2 and SpO2 95% vs. 90%). Alveolar recruitment maneuver use decreases the long term implications frequency in newborns with IRDS. CONCLUSIONS Alveolar recruitment maneuver is highly effective in newborns with IRDS. Its use decreases implications frequency and improves long term outcomes.

UI	MeSH Term	Description	Entries
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008297	Male		Males
D010100	Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.	Dioxygen,Oxygen-16,Oxygen 16
D011650	Pulmonary Alveoli	Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place.	Alveoli, Pulmonary,Alveolus, Pulmonary,Pulmonary Alveolus
D012123	Pulmonary Ventilation	The total volume of gas inspired or expired per unit of time, usually measured in liters per minute.	Respiratory Airflow,Ventilation Tests,Ventilation, Pulmonary,Expiratory Airflow,Airflow, Expiratory,Airflow, Respiratory,Test, Ventilation,Tests, Ventilation,Ventilation Test
D012127	Respiratory Distress Syndrome, Newborn	A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause.	Infantile Respiratory Distress Syndrome,Neonatal Respiratory Distress Syndrome,Respiratory Distress Syndrome, Infant
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000860	Hypoxia	Sub-optimal OXYGEN levels in the ambient air of living organisms.	Anoxia,Oxygen Deficiency,Anoxemia,Deficiency, Oxygen,Hypoxemia,Deficiencies, Oxygen,Oxygen Deficiencies
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective