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An 11 year-old girl was diagnosed as acute lymphoblastic leukemia (ALL) on November 26th 1979 and was induced into complete remission with vincristine and prednisolon. After consolidation therapy with daunomycin, vincristine and prednisolone, she developed pneumonia on January 21st 1980. No cause of pneumonia was found by sputum culture or serologic tests. Treatment with cefmetazol (CMZ), sulbenicillin (SBPC) and minocycline (MINO) was not effective but 9 g/day of LCM made a remarkable effect. Indirect immunofluorescence assay of antibody showed x 512 titers on January 22nd and in her recovery period, the titers showed eight times increased up to x 4,000. The diagnosis of Legionellosis was made on CDC's criteria. She recovered completely with sequential lincomycin (LCM) and erythromycin (EM) therapy. On October 1989, she is still in the first complete remission of ALL for more than 8 years.
N Tanabe, and
R Ohno, and
H Saito, and
E Nakura
January 1981,
Folia haematologica (Leipzig, Germany : 1928),
N Tanabe, and
R Ohno, and
H Saito, and
E Nakura
July 1986,
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society,
N Tanabe, and
R Ohno, and
H Saito, and
E Nakura
July 2017,
International journal of hygiene and environmental health,
N Tanabe, and
R Ohno, and
H Saito, and
E Nakura
January 1988,
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,
N Tanabe, and
R Ohno, and
H Saito, and
E Nakura
November 2003,
The New England journal of medicine,
N Tanabe, and
R Ohno, and
H Saito, and
E Nakura
May 2005,
Journal of pediatric hematology/oncology,
N Tanabe, and
R Ohno, and
H Saito, and
E Nakura
January 1989,
Bone marrow transplantation,
N Tanabe, and
R Ohno, and
H Saito, and
E Nakura
January 1988,
Medical and pediatric oncology,
N Tanabe, and
R Ohno, and
H Saito, and
E Nakura
January 1995,
Pediatric hematology and oncology,
N Tanabe, and
R Ohno, and
H Saito, and
E Nakura
December 2008,
Bangladesh Medical Research Council bulletin,
