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Responsiveness to leukotriene D4 and methacholine for predicting efficacy of montelukast in asthma. 2013
Wei-Jie Guan, and
Jin-Ping Zheng, and
Yi Gao, and
Cai-Yu Jiang, and
Yan-Qing Xie, and
Xu Shi, and
Zheng Zhu, and
Jia-Ying An, and
Xin-Xin Yu, and
Wen-Ting Liu, and
Nan-Shan Zhong
State Key Laboratory of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China;
A lower responsiveness to leukotriene D4 (LTD4) or higher LTD4/[methacholine (MCh)] potency ratio might suggest preferable outcomes of short-term montelukast monotherapy in terms of airway inflammation and lung function in asthmatic patients.
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