In this article we present three patients with atherosclerotic renal artery stenosis in a solitary kidney. They developed progressive renal failure, hypertension or fluid overload which were resistant to drug therapy. As there were no other therapeutic options they were treated with renal artery stenting, with good clinical results. Although large trials have not shown that endovascular stenting has any advantages over medical therapy in atherosclerotic renal artery stenosis, we propose that if other options fail there is a place for stenting in renal artery stenosis in patients with a single functioning kidney.