[Bonnecor--a new anti-arrhythmia preparation]. 1990

S Iu Berdiaev, and V V Lyskovtsev, and Z P Senova, and N V Darinskiĭ, and E K Grigor'eva, and E A Tolmacheva, and A I Turilova, and A N Gritsenko, and N V Kaverina

The antiarrhythmic properties of a new drug bonnecor being a derivative of dibenzazepine were studied on different models of arrhythmias. Bonnecor proved to be effective in the treatment of both atrial and ventricular arrhythmias of various genesis except rhythm disorders induced by ouabain intoxication. The drug was shown to exert a pronounced antifibrillatory effect and to increase the electrical stability of the intact and ischemic myocardium.

UI MeSH Term Description Entries
D009203 Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). Cardiovascular Stroke,Heart Attack,Myocardial Infarct,Cardiovascular Strokes,Heart Attacks,Infarct, Myocardial,Infarction, Myocardial,Infarctions, Myocardial,Infarcts, Myocardial,Myocardial Infarctions,Myocardial Infarcts,Stroke, Cardiovascular,Strokes, Cardiovascular
D011817 Rabbits A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes. Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D002415 Cats The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801) Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D003327 Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. Coronary Heart Disease,Coronary Diseases,Coronary Heart Diseases,Disease, Coronary,Disease, Coronary Heart,Diseases, Coronary,Diseases, Coronary Heart,Heart Disease, Coronary,Heart Diseases, Coronary
D003984 Dibenzazepines Compounds with two BENZENE rings fused to AZEPINES.
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D004305 Dose-Response Relationship, Drug The relationship between the dose of an administered drug and the response of the organism to the drug. Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D004353 Drug Evaluation, Preclinical Preclinical testing of drugs in experimental animals or in vitro for their biological and toxic effects and potential clinical applications. Drug Screening,Evaluation Studies, Drug, Pre-Clinical,Drug Evaluation Studies, Preclinical,Drug Evaluations, Preclinical,Evaluation Studies, Drug, Preclinical,Evaluation, Preclinical Drug,Evaluations, Preclinical Drug,Medicinal Plants Testing, Preclinical,Preclinical Drug Evaluation,Preclinical Drug Evaluations,Drug Screenings,Screening, Drug,Screenings, Drug
D006339 Heart Rate The number of times the HEART VENTRICLES contract per unit of time, usually per minute. Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D000157 Aconitine A C19 norditerpenoid alkaloid (DITERPENES) from the root of ACONITUM; DELPHINIUM and larkspurs. It activates VOLTAGE-GATED SODIUM CHANNELS. It has been used to induce ARRHYTHMIAS in experimental animals and it has anti-inflammatory and anti-neuralgic properties. Acetylbenzoylaconine,Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-,Acetylbenzoyl-aconine,Acetylbenzoyl aconine

Related Publications

S Iu Berdiaev, and V V Lyskovtsev, and Z P Senova, and N V Darinskiĭ, and E K Grigor'eva, and E A Tolmacheva, and A I Turilova, and A N Gritsenko, and N V Kaverina
January 1990, Farmakologiia i toksikologiia,
S Iu Berdiaev, and V V Lyskovtsev, and Z P Senova, and N V Darinskiĭ, and E K Grigor'eva, and E A Tolmacheva, and A I Turilova, and A N Gritsenko, and N V Kaverina
January 1990, Farmakologiia i toksikologiia,
S Iu Berdiaev, and V V Lyskovtsev, and Z P Senova, and N V Darinskiĭ, and E K Grigor'eva, and E A Tolmacheva, and A I Turilova, and A N Gritsenko, and N V Kaverina
December 1990, Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete,
S Iu Berdiaev, and V V Lyskovtsev, and Z P Senova, and N V Darinskiĭ, and E K Grigor'eva, and E A Tolmacheva, and A I Turilova, and A N Gritsenko, and N V Kaverina
January 1990, Farmakologiia i toksikologiia,
S Iu Berdiaev, and V V Lyskovtsev, and Z P Senova, and N V Darinskiĭ, and E K Grigor'eva, and E A Tolmacheva, and A I Turilova, and A N Gritsenko, and N V Kaverina
May 1989, Biulleten' eksperimental'noi biologii i meditsiny,
S Iu Berdiaev, and V V Lyskovtsev, and Z P Senova, and N V Darinskiĭ, and E K Grigor'eva, and E A Tolmacheva, and A I Turilova, and A N Gritsenko, and N V Kaverina
August 1986, Kardiologiia,
S Iu Berdiaev, and V V Lyskovtsev, and Z P Senova, and N V Darinskiĭ, and E K Grigor'eva, and E A Tolmacheva, and A I Turilova, and A N Gritsenko, and N V Kaverina
January 1993, Kardiologiia,
S Iu Berdiaev, and V V Lyskovtsev, and Z P Senova, and N V Darinskiĭ, and E K Grigor'eva, and E A Tolmacheva, and A I Turilova, and A N Gritsenko, and N V Kaverina
December 1996, Biulleten' eksperimental'noi biologii i meditsiny,
S Iu Berdiaev, and V V Lyskovtsev, and Z P Senova, and N V Darinskiĭ, and E K Grigor'eva, and E A Tolmacheva, and A I Turilova, and A N Gritsenko, and N V Kaverina
December 1989, Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete,
S Iu Berdiaev, and V V Lyskovtsev, and Z P Senova, and N V Darinskiĭ, and E K Grigor'eva, and E A Tolmacheva, and A I Turilova, and A N Gritsenko, and N V Kaverina
April 1985, Kardiologiia,
Copied contents to your clipboard!