BIOMAT Database Logo BIOMAT Database Logo

Whole genome sequencing of an unusual serotype of Shiga toxin-producing Escherichia coli. 2013

Tim Dallman, and Lisa Cross, and Chloe Bishop, and Neil Perry, and Bente Olesen, and Kathie A Grant, and Claire Jenkins
Health Protection Agency, London, UK.

Shiga toxin-producing Escherichia coli serotype O117:K1:H7 is a cause of persistent diarrhea in travelers to tropical locations. Whole genome sequencing identified genetic mechanisms involved in the pathoadaptive phenotype. Sequencing also identified toxin and putative adherence genes flanked by sequences indicating horizontal gene transfer from Shigella dysenteriae and Salmonella spp., respectively.

UI MeSH Term Description Entries
D010802 Phylogeny The relationships of groups of organisms as reflected by their genetic makeup. Community Phylogenetics,Molecular Phylogenetics,Phylogenetic Analyses,Phylogenetic Analysis,Phylogenetic Clustering,Phylogenetic Comparative Analysis,Phylogenetic Comparative Methods,Phylogenetic Distance,Phylogenetic Generalized Least Squares,Phylogenetic Groups,Phylogenetic Incongruence,Phylogenetic Inference,Phylogenetic Networks,Phylogenetic Reconstruction,Phylogenetic Relatedness,Phylogenetic Relationships,Phylogenetic Signal,Phylogenetic Structure,Phylogenetic Tree,Phylogenetic Trees,Phylogenomics,Analyse, Phylogenetic,Analysis, Phylogenetic,Analysis, Phylogenetic Comparative,Clustering, Phylogenetic,Community Phylogenetic,Comparative Analysis, Phylogenetic,Comparative Method, Phylogenetic,Distance, Phylogenetic,Group, Phylogenetic,Incongruence, Phylogenetic,Inference, Phylogenetic,Method, Phylogenetic Comparative,Molecular Phylogenetic,Network, Phylogenetic,Phylogenetic Analyse,Phylogenetic Clusterings,Phylogenetic Comparative Analyses,Phylogenetic Comparative Method,Phylogenetic Distances,Phylogenetic Group,Phylogenetic Incongruences,Phylogenetic Inferences,Phylogenetic Network,Phylogenetic Reconstructions,Phylogenetic Relatednesses,Phylogenetic Relationship,Phylogenetic Signals,Phylogenetic Structures,Phylogenetic, Community,Phylogenetic, Molecular,Phylogenies,Phylogenomic,Reconstruction, Phylogenetic,Relatedness, Phylogenetic,Relationship, Phylogenetic,Signal, Phylogenetic,Structure, Phylogenetic,Tree, Phylogenetic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012703 Serotyping Process of determining and distinguishing species of bacteria or viruses based on antigens they share. Serotypings
D016013 Likelihood Functions Functions constructed from a statistical model and a set of observed data which give the probability of that data for various values of the unknown model parameters. Those parameter values that maximize the probability are the maximum likelihood estimates of the parameters. Likelihood Ratio Test,Maximum Likelihood Estimates,Estimate, Maximum Likelihood,Estimates, Maximum Likelihood,Function, Likelihood,Functions, Likelihood,Likelihood Function,Maximum Likelihood Estimate,Test, Likelihood Ratio
D016680 Genome, Bacterial The genetic complement of a BACTERIA as represented in its DNA. Bacterial Genome,Bacterial Genomes,Genomes, Bacterial
D054323 Shiga-Toxigenic Escherichia coli Strains of ESCHERICHIA COLI with the ability to produce at least one or more of at least two antigenically distinct, usually bacteriophage-mediated cytotoxins: SHIGA TOXIN 1 and SHIGA TOXIN 2. These bacteria can cause severe disease in humans including bloody DIARRHEA and HEMOLYTIC UREMIC SYNDROME. E coli, Verotoxigenic,Escherichia coli, Verotoxigenic,STEC,Verotoxigenic Escherichia coli,Shiga Toxigenic E. coli,Shiga Toxigenic Escherichia coli,Shiga Toxin-Producing Escherichia coli,VTEC,Vero Cytotoxin-Producing Escherichia coli,Verotoxigenic E. coli,Verotoxin-Producing Escherichia coli
D058885 Multilocus Sequence Typing Direct nucleotide sequencing of gene fragments from multiple housekeeping genes for the purpose of phylogenetic analysis, organism identification, and typing of species, strain, serovar, or other distinguishable phylogenetic level. Multilocus Sequence Analysis,Analyses, Multilocus Sequence,Analysis, Multilocus Sequence,Multilocus Sequence Analyses,Sequence Analyses, Multilocus,Sequence Analysis, Multilocus,Sequence Typing, Multilocus,Typing, Multilocus Sequence
D059014 High-Throughput Nucleotide Sequencing Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc. High-Throughput Sequencing,Illumina Sequencing,Ion Proton Sequencing,Ion Torrent Sequencing,Next-Generation Sequencing,Deep Sequencing,High-Throughput DNA Sequencing,High-Throughput RNA Sequencing,Massively-Parallel Sequencing,Pyrosequencing,DNA Sequencing, High-Throughput,High Throughput DNA Sequencing,High Throughput Nucleotide Sequencing,High Throughput RNA Sequencing,High Throughput Sequencing,Massively Parallel Sequencing,Next Generation Sequencing,Nucleotide Sequencing, High-Throughput,RNA Sequencing, High-Throughput,Sequencing, Deep,Sequencing, High-Throughput,Sequencing, High-Throughput DNA,Sequencing, High-Throughput Nucleotide,Sequencing, High-Throughput RNA,Sequencing, Illumina,Sequencing, Ion Proton,Sequencing, Ion Torrent,Sequencing, Massively-Parallel,Sequencing, Next-Generation
D020641 Polymorphism, Single Nucleotide A single nucleotide variation in a genetic sequence that occurs at appreciable frequency in the population. SNPs,Single Nucleotide Polymorphism,Nucleotide Polymorphism, Single,Nucleotide Polymorphisms, Single,Polymorphisms, Single Nucleotide,Single Nucleotide Polymorphisms

Related Publications

Tim Dallman, and Lisa Cross, and Chloe Bishop, and Neil Perry, and Bente Olesen, and Kathie A Grant, and Claire Jenkins
Identification of Shiga Toxin-Producing Escherichia coli Outbreaks Using Whole Genome Sequencing.
January 2021, Methods in molecular biology (Clifton, N.J.),
Tim Dallman, and Lisa Cross, and Chloe Bishop, and Neil Perry, and Bente Olesen, and Kathie A Grant, and Claire Jenkins
Whole-genome sequencing for national surveillance of Shiga toxin-producing Escherichia coli O157.
August 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America,
Tim Dallman, and Lisa Cross, and Chloe Bishop, and Neil Perry, and Bente Olesen, and Kathie A Grant, and Claire Jenkins
Whole-Genome Sequencing of Shiga Toxin-Producing Escherichia coli for Characterization and Outbreak Investigation.
May 2023, Microorganisms,
Tim Dallman, and Lisa Cross, and Chloe Bishop, and Neil Perry, and Bente Olesen, and Kathie A Grant, and Claire Jenkins
Whole-genome sequencing for risk assessment of long-term Shiga toxin-producing Escherichia coli.
April 2014, Emerging infectious diseases,
Tim Dallman, and Lisa Cross, and Chloe Bishop, and Neil Perry, and Bente Olesen, and Kathie A Grant, and Claire Jenkins
Phylogenetic analysis of non-O157 Shiga toxin-producing Escherichia coli strains by whole-genome sequencing.
December 2012, Journal of clinical microbiology,
Tim Dallman, and Lisa Cross, and Chloe Bishop, and Neil Perry, and Bente Olesen, and Kathie A Grant, and Claire Jenkins
Transforming Shiga toxin-producing Escherichia coli surveillance through whole genome sequencing in food safety practices.
January 2023, Frontiers in microbiology,
Tim Dallman, and Lisa Cross, and Chloe Bishop, and Neil Perry, and Bente Olesen, and Kathie A Grant, and Claire Jenkins
Whole genome sequencing to characterize shiga toxin-producing Escherichia coli O26 in a public health setting.
January 2019, Journal of infection and public health,
Tim Dallman, and Lisa Cross, and Chloe Bishop, and Neil Perry, and Bente Olesen, and Kathie A Grant, and Claire Jenkins
Whole Genome Sequencing Characterization of Shiga Toxin-Producing Escherichia coli Isolated from Flour from Swiss Retail Markets.
August 2019, Journal of food protection,
Tim Dallman, and Lisa Cross, and Chloe Bishop, and Neil Perry, and Bente Olesen, and Kathie A Grant, and Claire Jenkins
Whole Genome Sequencing for Public Health Surveillance of Shiga Toxin-Producing Escherichia coli Other than Serogroup O157.
January 2016, Frontiers in microbiology,
Tim Dallman, and Lisa Cross, and Chloe Bishop, and Neil Perry, and Bente Olesen, and Kathie A Grant, and Claire Jenkins
Whole-Genome Sequencing of Shiga Toxin-Producing Escherichia coli OX18 from a Fatal Hemolytic Uremic Syndrome Case.
May 2021, Emerging infectious diseases,
Copied contents to your clipboard!