-transparent.png){kind=logo}
Curcumin (Cur) has putative antitumor properties. In the current study, we examined photophysical and photochemical properties of Cur using laser flash photolysis. The results demonstrated that Cur could be photo-ionized at 355 nm laser pulse to produce radical cation (Cur(+)) and solvated electron e(sol)(-) in 7:3 ethanol-water mixtures. The quantum yield of Cur photo-ionization and the ratio of photo-ionization to photo-excitation were also determined. Cur(+) could be transferred into neutral radical of Cur (Cur) via deprotonation with the pKa 4.13. The excited singlet of Cur ((1)Cur* could be transferred into excited triplet ((3)Cur*, which could be quenched by oxygen to produce singlet oxygen (1)O2*. Reaction of (3)Cur* with tryptophan was confirmed. The results encourage developing curcumin as a photosensitive antitumor agent.
Tingting Qian, and
Li Kun, and
Bo Gao, and
Rongrong Zhu, and
Xianzheng Wu, and
Shilong Wang
April 2016,
Physical chemistry chemical physics : PCCP,
Tingting Qian, and
Li Kun, and
Bo Gao, and
Rongrong Zhu, and
Xianzheng Wu, and
Shilong Wang
December 2001,
Photochemistry and photobiology,
Tingting Qian, and
Li Kun, and
Bo Gao, and
Rongrong Zhu, and
Xianzheng Wu, and
Shilong Wang
January 1973,
Anais da Academia Brasileira de Ciencias,
Tingting Qian, and
Li Kun, and
Bo Gao, and
Rongrong Zhu, and
Xianzheng Wu, and
Shilong Wang
March 1977,
Photochemistry and photobiology,
Tingting Qian, and
Li Kun, and
Bo Gao, and
Rongrong Zhu, and
Xianzheng Wu, and
Shilong Wang
November 2003,
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology,
Tingting Qian, and
Li Kun, and
Bo Gao, and
Rongrong Zhu, and
Xianzheng Wu, and
Shilong Wang
September 2003,
Organic letters,
Tingting Qian, and
Li Kun, and
Bo Gao, and
Rongrong Zhu, and
Xianzheng Wu, and
Shilong Wang
April 2000,
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,
Tingting Qian, and
Li Kun, and
Bo Gao, and
Rongrong Zhu, and
Xianzheng Wu, and
Shilong Wang
April 1967,
Photochemistry and photobiology,
Tingting Qian, and
Li Kun, and
Bo Gao, and
Rongrong Zhu, and
Xianzheng Wu, and
Shilong Wang
August 1977,
Biochemical and biophysical research communications,
Tingting Qian, and
Li Kun, and
Bo Gao, and
Rongrong Zhu, and
Xianzheng Wu, and
Shilong Wang
May 1978,
Photochemistry and photobiology,
