BIOMAT Database Logo BIOMAT Database Logo

[Detection of specific IgM in the CSF for early and rapid diagnosis of herpes simplex virus encephalitis]. 1990

H M Mo, and L B Zhang
Institute of Virology, Chinese Academy of preventive Medicine, Beijing.

A capture-ELISA for detecting IgM in CSF was developed for the purpose of rapid and early diagnosis of herpes simplex virus (HSV) encephalitis. In 37 cases with sporadic HSV encephalitis the CSF IgM was measured. In 13 cases the results were positive, in the others it was negative. 17 cases with other central nervous system disorders were taken as control group in which only one case with Guillain-Barré syndrome showed positive test and all the others were HSV antibody negative except one with IgG positive in CSF who had undergone a brain operation two weeks prior to the test.

UI MeSH Term Description Entries
D007075 Immunoglobulin M A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally was called a macroglobulin. Gamma Globulin, 19S,IgM,IgM Antibody,IgM1,IgM2,19S Gamma Globulin,Antibody, IgM
D007223 Infant A child between 1 and 23 months of age. Infants
D008297 Male Males
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D004660 Encephalitis Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition. Inflammation, Brain,Rasmussen Syndrome,Brain Inflammation,Encephalitis, Rasmussen,Rasmussen Encephalitis,Rasmussen's Syndrome,Brain Inflammations
D005260 Female Females
D006561 Herpes Simplex A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.) Herpes Simplex Virus Infection
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

H M Mo, and L B Zhang
Herpes simplex virus encephalitis: the need for early diagnosis.
January 1986, North Carolina medical journal,
H M Mo, and L B Zhang
Obstacle to early diagnosis of herpes simplex encephalitis via CSF.
July 1990, Lancet (London, England),
H M Mo, and L B Zhang
Obstacle to early diagnosis of herpes simplex encephalitis via CSF.
August 1990, Lancet (London, England),
H M Mo, and L B Zhang
Herpes simplex virus-IgM specific antibodies in Guillain-Barré syndrome and encephalitis.
September 1977, Acta neurologica Scandinavica,
H M Mo, and L B Zhang
Demonstration of herpes simplex virus DNA in CSF cells by in situ hybridization for early diagnosis of herpes encephalitis.
April 1990, Journal of neurology,
H M Mo, and L B Zhang
[Early diagnosis of herpes simplex virus encephalitis in childhood].
September 1985, No to hattatsu = Brain and development,
H M Mo, and L B Zhang
Early intrathecal production of specific IgM and IgG antibodies and alpha-interferon in herpes simplex virus encephalitis.
March 1986, Acta virologica,
H M Mo, and L B Zhang
Rapid detection of herpes-simplex-virus DNA in cerebrospinal fluid of patients with herpes simplex encephalitis.
February 1990, Lancet (London, England),
H M Mo, and L B Zhang
Diagnosis of Herpes simplex virus encephalitis.
October 1982, JAMA,
H M Mo, and L B Zhang
Diagnosis of herpes simplex virus encephalitis.
September 1992, Developmental medicine and child neurology,
Copied contents to your clipboard!