Biomaterial Database

[Relation of circulating immunocomplexes and epileptic discharges in the electroencephalograms (EEG) of epileptic patients]. 1990

J Yang

Neurological Research Unit, Affiliated Hospital of Qingdao Medical College.

The relation between the EEG manifestations and the contents of the circulating immune complexes (CIC) in 160 epileptic patients was studied. It was found that the CIC contents of the patients with epileptic discharges (P less than 0.01). It was not related to the sexual distinction, age, type of seizures frequency of attacks treatment, and length of the time between the last attacks and the time for the measurements. Even in the same patient, the CIC content would be at a high level when epileptic discharges appeared, and decreased when epileptic discharges disappeared in the EEG observed. It was surmised that this might be due to some biological active factors released during the epileptic discharges of the brain which destroyed the integrity of the blood brain barrier so that large quantity of brain antigen entered the systemic circulation and combine with corresponding antibodies thus leading to the increase of CIC.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D004569	Electroencephalography	Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.	EEG,Electroencephalogram,Electroencephalograms
D004827	Epilepsy	A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)	Aura,Awakening Epilepsy,Seizure Disorder,Epilepsy, Cryptogenic,Auras,Cryptogenic Epilepsies,Cryptogenic Epilepsy,Epilepsies,Epilepsies, Cryptogenic,Epilepsy, Awakening,Seizure Disorders
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults