Biomaterial Database

Laryngotracheal reconstruction for relapsing polychondritis: case report and review of the literature. 2013

C Xie, and N Shah, and P L Shah, and G Sandhu

ENT Department, Charing Cross Hospital, Imperial College Trust, London, UK.

BACKGROUND Relapsing polychondritis is a multi-system autoimmune disease characterised by the inflammation and destruction of cartilaginous structures. The most common sites are the pinna, nose, laryngotracheobronchial tree and peripheral joints. Airway involvement occurs in up to half of patients affected, at any disease stage. It is the most severe and life-threatening aspect of the disease, and proves to be a therapeutic challenge. OBJECTIVE This article reports our experience of performing laryngotracheal reconstruction in a patient with relapsing polychondritis. A review of the literature is presented, with a focused discussion of airway treatment options. METHODS Laryngotracheal reconstruction for relapsing polychondritis was performed using hyoid bone pedicled on sternohyoid muscle. CONCLUSIONS Airway management in relapsing polychondritis can improve quality of life and palliate patients effectively.

UI	MeSH Term	Description	Entries
D007818	Laryngeal Diseases	Pathological processes involving any part of the LARYNX which coordinates many functions such as voice production, breathing, swallowing, and coughing.	Laryngeal Perichondritis,Larynx Diseases,Disease, Laryngeal,Disease, Larynx,Diseases, Laryngeal,Diseases, Larynx,Laryngeal Disease,Laryngeal Perichondritides,Larynx Disease,Perichondritides, Laryngeal,Perichondritis, Laryngeal
D008297	Male		Males
D011081	Polychondritis, Relapsing	An acquired disease of unknown etiology, chronic course, and tendency to recur. It is characterized by inflammation and degeneration of cartilage and can result in deformities such as floppy ear and saddle nose. Loss of cartilage in the respiratory tract can lead to respiratory obstruction.	Polychondritis, Chronic Atrophic,Atrophic Polychondritides, Chronic,Atrophic Polychondritis, Chronic,Chronic Atrophic Polychondritides,Chronic Atrophic Polychondritis,Polychondritides, Chronic Atrophic,Polychondritides, Relapsing,Relapsing Polychondritides,Relapsing Polychondritis
D011788	Quality of Life	A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral, social environment as well as health and disease.	HRQOL,Health-Related Quality Of Life,Life Quality,Health Related Quality Of Life
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006928	Hyoid Bone	A mobile U-shaped bone that lies in the anterior part of the neck at the level of the third CERVICAL VERTEBRAE. The hyoid bone is suspended from the processes of the TEMPORAL BONES by ligaments, and is firmly bound to the THYROID CARTILAGE by muscles.	Lingual Bone,Bone, Hyoid,Bone, Lingual,Bones, Hyoid,Bones, Lingual,Hyoid Bones,Lingual Bones
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D013517	Otorhinolaryngologic Surgical Procedures	Surgery performed on the ear and its parts, the nose and nasal cavity, or the throat, including surgery of the adenoids, tonsils, pharynx, and trachea.	Otorhinolaryngologic Surgical Procedure,Otorhinolaryngological Surgical Procedures,Procedure, Otorhinolaryngologic Surgical,Procedures, Otorhinolaryngologic Surgical,Surgical Procedure, Otorhinolaryngologic,Surgical Procedures, Otorhinolaryngologic,Otorhinolaryngological Surgical Procedure,Procedure, Otorhinolaryngological Surgical,Procedures, Otorhinolaryngological Surgical,Surgical Procedure, Otorhinolaryngological,Surgical Procedures, Otorhinolaryngological
D014133	Tracheal Diseases	Diseases involving the TRACHEA.	Disease, Tracheal,Diseases, Tracheal,Tracheal Disease
D056151	Airway Remodeling	The structural changes in the number, mass, size and/or composition of the airway tissues.	Airway Remodelling,Asthmatic Airway Remodeling,Asthmatic Airway Remodelling,Asthmatic Airway Wall Remodeling,Asthmatic Airway Wall Remodelling,Small Airway Remodeling,Small Airway Remodelling,Airway Wall Remodelling,Airway Remodeling, Asthmatic,Airway Remodeling, Small,Airway Remodelings,Airway Remodelings, Asthmatic,Airway Remodelings, Small,Airway Remodelling, Asthmatic,Airway Remodelling, Small,Airway Remodellings,Airway Remodellings, Asthmatic,Airway Remodellings, Small,Airway Wall Remodellings,Asthmatic Airway Remodelings,Asthmatic Airway Remodellings,Remodeling, Airway,Remodeling, Asthmatic Airway,Remodeling, Small Airway,Remodelings, Airway,Remodelings, Asthmatic Airway,Remodelings, Small Airway,Remodelling, Airway,Remodelling, Airway Wall,Remodelling, Asthmatic Airway,Remodelling, Small Airway,Remodellings, Airway,Remodellings, Airway Wall,Remodellings, Asthmatic Airway,Remodellings, Small Airway,Small Airway Remodelings,Small Airway Remodellings,Wall Remodelling, Airway,Wall Remodellings, Airway